SCHEMBL22041533

SCHEMBL22041533

Cc1ccc(-c2ccccc2C(=O)P(=O)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
L3MBTL1 Q9Y468 1/20 0.43
ALDH1A1 P00352 1/20 0.43
LMNA P02545 3/20 0.43
BCAT2 O15382 1/20 0.42
LTB4R2 Q9NPC1 3/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
GAA P10253 2/20 0.42
CHRNB2 P17787 1/20 0.41
CHRNB4 P30926 1/20 0.41
CHRNA3 P32297 1/20 0.41
CHRNA4 P43681 1/20 0.41
HDAC7 Q8WUI4 1/20 0.41
POLB P06746 1/20 0.40
TP53 P04637 1/20 0.40
NFKB1 P19838 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4181722 0.89 BCAT2 (0.53) KMT2AMEN1SMN1; SMN2ALDH1A1LMNA
SCHEMBL21880221 0.79 MYC (0.47) L3MBTL1ALDH1A1LMNARAB9APOLB
SCHEMBL23902980 0.79 LMNA (0.52) KMT2AMEN1SMN1; SMN2ALDH1A1LMNA
SCHEMBL31402608 0.78 KMT2A (0.60) KMT2AMEN1SMN1; SMN2ALDH1A1BCAT2
SCHEMBL372 0.78 KMT2A (0.60) KMT2AMEN1SMN1; SMN2ALDH1A1BCAT2
SCHEMBL17023658 0.77 CA2 (0.48) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1
SCHEMBL57823 0.76 HPGD (0.50) KMT2ASMN1; SMN2ALDH1A1LMNANPC1
SCHEMBL83199 0.76 LMNA (0.56) KMT2AMEN1SMN1; SMN2ALDH1A1LMNA
Hydrochloric Acid SCHEMBL7610390 0.76 KMT2A (0.59) KMT2AMEN1SMN1; SMN2ALDH1A1BCAT2
SCHEMBL16882044 0.76 KMT2A (0.48) KMT2AMEN1SMN1; SMN2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113454095-B Acylphosphino-oxygen compound and preparation method thereof 安庆莱霆光电科技有限公司 2023-08-22 CN disclosed
CN-113454095-A Acylphosphinoxide compound and preparation method thereof 安庆莱霆光电科技有限公司 2021-09-28 CN disclosed
WO-2020113585-A1 ACYLPHOSPHINE OXIDE COMPOUND AND PREPARATION METHOD THEREFOR 安庆莱霆光电科技有限公司 2020-06-11 WO disclosed