Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18209598 | 0.88 | RAB9A (0.69) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL9699014 | 0.84 | ALDH1A1 (0.64) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL19124560 | 0.82 | LMNA (0.54) | ALDH1A1MAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL22041562 | 0.79 | CES2 (0.56) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL1646005 | 0.78 | ALDH1A1 (0.52) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL4755625 | 0.78 | ALDH1A1 (0.50) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL23902975 | 0.77 | PLK1 (0.42) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL21359733 | 0.77 | CYP2C9 (0.44) | ALDH1A1HPGDRAB9ANPC1KMT2A | |
| SCHEMBL10582312 | 0.75 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPTRAB9ANPC1 | |
| SCHEMBL8647089 | 0.75 | MAPT (0.62) | ALDH1A1HPGDMAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113454095-B | Acylphosphino-oxygen compound and preparation method thereof | 安庆莱霆光电科技有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-113454095-A | Acylphosphinoxide compound and preparation method thereof | 安庆莱霆光电科技有限公司 | 2021-09-28 | — | — | CN | disclosed |
| WO-2020113585-A1 | ACYLPHOSPHINE OXIDE COMPOUND AND PREPARATION METHOD THEREFOR | 安庆莱霆光电科技有限公司 | 2020-06-11 | — | — | WO | disclosed |