⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22057304 | 0.87 | LOXL2 (0.30) | — | |
| SCHEMBL14045542 | 0.68 | LMNA (0.38) | — | |
| SCHEMBL14045513 | 0.67 | LMNA (0.45) | — | |
| SCHEMBL12231940 | 0.65 | — | — | |
| SCHEMBL22057392 | 0.61 | — | — | |
| SCHEMBL2830638 | 0.60 | LMNA (0.73) | — | |
| SCHEMBL22057303 | 0.59 | KMT2A (0.33) | — | |
| SCHEMBL2323293 | 0.59 | OXER1 (0.32) | — | |
| SCHEMBL7454280 | 0.59 | LMNA (0.53) | — | |
| SCHEMBL25550059 | 0.58 | TBXAS1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11135319-B2 | Compounds useful as imaging agents of hypoxia | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-10-05 | — | — | US | disclosed |
| US-20200171178-A1 | COMPOUNDS USEFUL AS IMAGING AGENTS OF HYPOXIA | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-06-04 | — | — | US | disclosed |