Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844954 | 0.76 | CYP1A2 (0.54) | NQO2MAPTLMNANPC1RAB9A | |
| SCHEMBL29639043 | 0.76 | CYP1A2 (0.54) | NQO2MAPTLMNANPC1RAB9A | |
| SCHEMBL7048629 | 0.76 | NCF1 (0.55) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL23229346 | 0.75 | NCF1 (0.59) | NQO2MAPTLMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28590788 | 0.75 | NCF1 (0.53) | MAPTNPC1RAB9AMAPK1SMN1; SMN2 | |
| SCHEMBL31143623 | 0.73 | CYP1A2 (0.59) | NQO2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8275784 | 0.73 | CYP1A2 (0.59) | NQO2NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14330664 | 0.73 | NQO2 (0.50) | NQO2MAPTLMNANPC1RAB9A | |
| SCHEMBL19001484 | 0.73 | NQO2 (0.50) | NQO2MAPTLMNANPC1RAB9A | |
| SCHEMBL557898 | 0.73 | ALDH1A1 (0.62) | NQO2MAPTLMNANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3659597-A2 | COMPOSITIONS AND METHODS FOR DRUG SENSITIZATION OF PARASITES | The Texas A&M University System (US) | 2020-06-03 | — | — | EP | disclosed |