Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258411 | 0.76 | ALDH1A1 (0.39) | MAPTTP53ALDH1A1HPGDMEN1 | |
| SCHEMBL18576288 | 0.72 | MAOA (0.42) | MAOAMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL2378021 | 0.72 | MAPT (0.44) | MAPTTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL2163313 | 0.71 | MAPT (0.40) | MAPTTP53ALDH1A1HPGDMEN1 | |
| SCHEMBL4633992 | 0.70 | RET (0.34) | MAPTTP53ALDH1A1HPGDMEN1 | |
| SCHEMBL10634839 | 0.70 | ACHE (0.36) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL28154129 | 0.70 | LMNA (0.36) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9228130 | 0.70 | ALDH1A1 (0.39) | MAPTTP53ALDH1A1HPGDMEN1 | |
| SCHEMBL12778762 | 0.69 | MAOA (0.40) | MAOAMAPTALDH1A1HPGDMEN1 | |
| SCHEMBL22962312 | 0.67 | KDM4E (0.41) | MAOAMAPTALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3139919-B1 | COMPOUNDS FOR TREATMENT OF CANCER | ONCTERNAL THERAPEUTICS INC (US) | 2020-06-03 | — | — | EP | disclosed |