SCHEMBL22062774

SCHEMBL22062774

c1ccc2cc(-c3c4ccccc4c(-c4ccc5cc(-c6ccc7oc8ccccc8c7c6)ccc5c4)c4ccccc34)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.46
NPC1 O15118 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HPGD P15428 2/20 0.46
RAB9A P51151 2/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CASP3 P42574 1/20 0.45
SENP7 Q9BQF6 1/20 0.45
SENP6 Q9GZR1 1/20 0.45
AHR P35869 2/20 0.42
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
PLA2G2A P14555 2/20 0.40
PLA2G4A P47712 2/20 0.40
GLA P06280 1/20 0.40
TSHR P16473 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124676 0.98 MAPT (0.47) MAPTNPC1KDM4EHPGDRAB9A
SCHEMBL29875299 0.98 MAPT (0.47) MAPTNPC1KDM4EHPGDRAB9A
SCHEMBL124820 0.97 MAPT (0.44) MAPTNPC1KDM4EHPGDRAB9A
SCHEMBL22916712 0.97 MAPT (0.44) MAPTNPC1KDM4EHPGDRAB9A
SCHEMBL22916861 0.97 MAPT (0.44) MAPTNPC1KDM4EHPGDRAB9A
SCHEMBL23096913 0.97 PLA2G2A (0.44) MAPTNPC1KDM4EHPGDRAB9A
SCHEMBL12577590 0.97 MAPT (0.44) MAPTNPC1KDM4EHPGDRAB9A
SCHEMBL24024559 0.97 MAPT (0.44) MAPTNPC1KDM4EHPGDRAB9A
SCHEMBL124682 0.97 MAPT (0.44) MAPTNPC1KDM4EHPGDRAB9A
SCHEMBL12577934 0.97 MAPT (0.44) MAPTNPC1KDM4EHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11665962-B2 Organic electroluminescence element and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2023-05-30 US disclosed
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-14 US disclosed
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2020-07-02 US disclosed
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE OLA1, TAS2R19, TMEM109 MAPT 2477/4885NPC1 3340/4885KDM4E 1466/4885
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND OR10J3, ESR1, NFE2L2 MAPT 3295/4885NPC1 3282/4885KDM4E 2780/4885
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE AHR, EMC2, NFE2L2 MAPT 2800/4885NPC1 2986/4885KDM4E 1043/4885
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE EMC2, NFE2L2, AOC2 MAPT 2667/4885NPC1 2661/4885KDM4E 1152/4885
US-11665962-B2 Organic electroluminescence element and electronic device ESR1, EML4, L1CAM MAPT 958/4885NPC1 2699/4885KDM4E 1950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.