SCHEMBL22062776

SCHEMBL22062776

c1cc(-c2ccc3c(c2)oc2ccccc23)cc(-c2c3ccccc3c(-c3cccc4ccccc34)c3ccccc23)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 2/20 0.41
HCRTR1 O43613 1/20 0.40
PLA2G2A P14555 2/20 0.40
PLA2G4A P47712 2/20 0.40
DUSP3 P51452 1/20 0.40
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
MEN1 O00255 1/20 0.40
MAPT P10636 1/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 1/20 0.40
PSD A5PKW4 1/20 0.39
ALOX5 P09917 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
PLA2G10 O15496 1/20 0.37
MMP12 P39900 1/20 0.37
MMP13 P45452 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17945599 0.97 HCRTR1 (0.39) AHRHCRTR1PLA2G2APLA2G4ADUSP3
SCHEMBL17932142 0.96 HCRTR1 (0.38) AHRHCRTR1PLA2G2APLA2G4ADUSP3
SCHEMBL1687675 0.96 AHR (0.44) AHRHCRTR1DUSP3KDM4EALDH1A1
SCHEMBL4079303 0.95 HCRTR1 (0.39) AHRHCRTR1PLA2G2APLA2G4ADUSP3
SCHEMBL22903480 0.94 AHR (0.42) AHRHCRTR1DUSP3KDM4EALDH1A1
SCHEMBL24340995 0.93 ALOX5 (0.45) HCRTR1PLA2G2APLA2G4ADUSP3KDM4E
SCHEMBL22854822 0.93 HCRTR1 (0.38) AHRHCRTR1PLA2G2APLA2G4ADUSP3
SCHEMBL17945294 0.93 HCRTR1 (0.38) AHRHCRTR1PLA2G2APLA2G4ADUSP3
SCHEMBL24285562 0.93 HSD17B1 (0.41) AHRHCRTR1PLA2G2APLA2G4ADUSP3
SCHEMBL23056895 0.93 MMP12 (0.40) AHRHCRTR1PLA2G2APLA2G4ADUSP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230329025-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-10-12 US disclosed
US-20230329025-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-10-12 US disclosed
WO-2023190597-A1 ORGANIC ELECTROLUMINESCENT ELEMENT AND ELECTRONIC DEVICE 出光興産株式会社 2023-10-05 WO disclosed
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE EMC2, NFE2L2, AOC2 AHR 8/4885HCRTR1 1985/4885PLA2G2A 4685/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.