SCHEMBL22062783

SCHEMBL22062783

c1ccc2cc(-c3c4ccccc4c(-c4ccc(-c5ccc6oc7cc8ccccc8cc7c6c5)c5ccccc45)c4ccccc34)ccc2c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 2/20 0.39
GSTP1 P09211 1/20 0.38
MIF P14174 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
KDM4E B2RXH2 7/20 0.35
MAPT P10636 5/20 0.35
HPGD P15428 4/20 0.35
TSHR P16473 3/20 0.35
HSD17B10 Q99714 2/20 0.35
GLA P06280 2/20 0.35
HTT P42858 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
CASP3 P42574 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16067731 1.00 GPR84 (0.39) GPR84GSTP1MIFHDAC4HDAC2
SCHEMBL22062641 0.96 HDAC4 (0.38) GPR84GSTP1MIFHDAC4HDAC2
SCHEMBL19080082 0.94 GSTP1 (0.40) GPR84GSTP1MIFHDAC4HDAC2
SCHEMBL17932067 0.94 PGR (0.40) GPR84KDM4EMAPTHPGDTSHR
SCHEMBL22063394 0.93 MAPT (0.41) GPR84GSTP1MIFHDAC4HDAC2
SCHEMBL21881120 0.93 MAPT (0.41) GPR84GSTP1MIFHDAC4HDAC2
SCHEMBL19076494 0.92 AHR (0.38) GPR84GSTP1MIFHDAC4HDAC2
SCHEMBL20127571 0.92 GPR84 (0.39) GPR84GSTP1MIFHDAC4HDAC2
SCHEMBL22062640 0.92 HDAC4 (0.39) GPR84GSTP1MIFHDAC4HDAC2
SCHEMBL16067655 0.92 KDM4E (0.40) GPR84GSTP1KDM4EMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-14 US disclosed
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2020-07-02 US disclosed
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE OLA1, TAS2R19, TMEM109 GPR84 228/4885GSTP1 4451/4885MIF 4660/4885
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND OR10J3, ESR1, NFE2L2 GPR84 2936/4885GSTP1 2860/4885MIF 3996/4885
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE AHR, EMC2, NFE2L2 GPR84 3433/4885GSTP1 3751/4885MIF 3806/4885
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE EMC2, NFE2L2, AOC2 GPR84 3690/4885GSTP1 3440/4885MIF 3699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.