SCHEMBL22062786

SCHEMBL22062786

c1ccc2cc(-c3c4ccccc4c(-c4ccc5cc(-c6ccc7oc8cc9ccccc9cc8c7c6)ccc5c4)c4ccccc34)ccc2c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP3 P42574 1/20 0.41
SENP7 Q9BQF6 1/20 0.41
SENP6 Q9GZR1 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
KDM4E B2RXH2 5/20 0.39
MAPT P10636 3/20 0.39
HPGD P15428 3/20 0.39
GLA P06280 2/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
ALOX5 P09917 2/20 0.39
CYP1A1 P04798 1/20 0.38
CYP1B1 Q16678 1/20 0.38
HCRTR1 O43613 1/20 0.38
HNF4A P41235 1/20 0.38
ALDH1A1 P00352 4/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16067752 1.00 CASP3 (0.41) CASP3SENP7SENP6ESR1ESR2
SCHEMBL16067655 0.98 KDM4E (0.40) CASP3SENP7SENP6ESR1ESR2
SCHEMBL17122671 0.97 CYP1A1 (0.40) CASP3SENP7SENP6ESR1ESR2
SCHEMBL16067646 0.97 ESR1 (0.41) CASP3SENP7SENP6ESR1ESR2
SCHEMBL21928967 0.97 ESR1 (0.41) CASP3SENP7SENP6ESR1ESR2
SCHEMBL24024568 0.97 CYP1A1 (0.40) CASP3SENP7SENP6ESR1ESR2
SCHEMBL16067704 0.97 ESR1 (0.41) CASP3SENP7SENP6ESR1ESR2
SCHEMBL22217972 0.97 KDM4E (0.39) CASP3SENP7SENP6ESR1ESR2
SCHEMBL21450726 0.97 KDM4E (0.41) CASP3SENP7SENP6ESR1ESR2
SCHEMBL16067926 0.96 HSD17B1 (0.41) CASP3SENP7SENP6ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-14 US disclosed
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND IDEMITSU KOSAN CO.,LTD. (JP) 2020-07-02 US disclosed
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE OLA1, TAS2R19, TMEM109 CASP3 4822/4885SENP7 4518/4885SENP6 3841/4885
US-20200212315-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND OR10J3, ESR1, NFE2L2 CASP3 4173/4885SENP7 4782/4885SENP6 4332/4885
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE AHR, EMC2, NFE2L2 CASP3 3135/4885SENP7 3985/4885SENP6 4519/4885
US-20200185620-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE EMC2, NFE2L2, AOC2 CASP3 3430/4885SENP7 4449/4885SENP6 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.