Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 8/20 | 0.47 |
| ▸ | NOS1 | P29475 | 7/20 | 0.47 |
| ▸ | NOS3 | P29474 | 4/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21444983 | 1.00 | NOS2 (0.47) | NOS2NOS1NOS3TAAR1ALDH1A1 | |
| SCHEMBL27572549 | 0.85 | TAAR1 (0.49) | NOS2NOS1TAAR1 | |
| SCHEMBL24802686 | 0.85 | NOS2 (0.45) | NOS2NOS1NOS3TAAR1ALDH1A1 | |
| SCHEMBL10616856 | 0.84 | NOS2 (0.44) | NOS2NOS1NOS3TAAR1ALDH1A1 | |
| SCHEMBL7091189 | 0.81 | NOS2 (0.41) | NOS2NOS1NOS3TAAR1ALDH1A1 | |
| SCHEMBL26107976 | 0.81 | NOS2 (0.42) | NOS2NOS1NOS3TAAR1 | |
| SCHEMBL7854852 | 0.80 | ALDH1A1 (0.41) | NOS2NOS1NOS3TAAR1ALDH1A1 | |
| SCHEMBL7651855 | 0.80 | ALDH1A1 (0.41) | NOS2NOS1NOS3TAAR1ALDH1A1 | |
| SCHEMBL7857240 | 0.80 | ALDH1A1 (0.41) | NOS2NOS1NOS3TAAR1ALDH1A1 | |
| SCHEMBL7846606 | 0.80 | ALDH1A1 (0.41) | NOS2NOS1NOS3TAAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691958-B2 | Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions | NORTHWESTERN UNIVERSITY (US) | 2023-07-04 | — | — | US | disclosed |
| US-20200181106-A1 | ENANTIOSELECTIVE CROSS DEHYDROGENATIVE COUPLING REACTIONS AND COMPOUNDS SYNTHESIZED BY THE REACTIONS | NORTHWESTERN UNIVERSITY (US) | 2020-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691958-B2 | Enantioselective cross dehydrogenative coupling reactions and compounds synthesized by the reactions | DUOX1, DUOX2, ALDH3A1 | NOS2 2202/4885NOS1 2599/4885NOS3 2949/4885 |
| US-20200181106-A1 | ENANTIOSELECTIVE CROSS DEHYDROGENATIVE COUPLING REACTIONS AND COMPOUNDS SYNTHESIZED BY THE REACTIONS | DUOX1, DUOX2, ALDH3A1 | NOS2 2202/4885NOS1 2599/4885NOS3 2949/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.