SCHEMBL486687

SCHEMBL486687

O=C1CCN(CCc2ccccc2)CC1

nearest known ligand 0.70

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 1/20 0.66
SIGMAR1 Q99720 2/20 0.63
HTR1A P08908 1/20 0.58
DRD2 P14416 1/20 0.58
ACHE P22303 1/20 0.56
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
CCR3 P51677 1/20 0.54
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
KCNH2 Q12809 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8108965 1.00 SLC6A3 (0.66) SLC6A3SIGMAR1HTR1ADRD2ACHE
Hydrochloric Acid SCHEMBL486705 0.98 SLC6A3 (0.63) SLC6A3SIGMAR1HTR1ADRD2ACHE
Iodide SCHEMBL195620 0.98 SLC6A3 (0.63) SLC6A3SIGMAR1HTR1ADRD2ACHE
Hydrochloric Acid SCHEMBL7810971 0.92 SLC6A3 (0.66) SLC6A3SIGMAR1HTR1ADRD2NPC1
SCHEMBL3959376 0.89 SIGMAR1 (0.72) SIGMAR1CCR3
SCHEMBL21047654 0.89 SLC6A3 (0.56) SLC6A3SIGMAR1HTR1ADRD2ACHE
SCHEMBL6705256 0.87 SIGMAR1 (0.67) SIGMAR1CCR3MEN1KMT2A
SCHEMBL5612374 0.86 SIGMAR1 (0.70) SIGMAR1CCR3MEN1KMT2A
SCHEMBL14407778 0.83 SLC6A3 (0.83) SLC6A3SIGMAR1HTR1ADRD2ACHE
SCHEMBL6056974 0.83 SLC6A3 (0.83) SLC6A3SIGMAR1HTR1ADRD2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 501 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12340996-B2 Method for rapid on-site detection of fentanyl analogs using a miniature mass spectrometer CHINESE ACADEMY OF INSPECTION AND QUARANTINE (CN) 2025-06-24 US claimed
US-20250189547-A1 SURFACE-ENHANCED RAMAN NANOPARTICLE AND DETECTION METHOD FOR FENTANYLS Shenzhen Customs Industrial Products Testing Technology Center (CN) 2025-06-12 US claimed
CN-117664949-A Detection method of surface-enhanced Raman nano particles and fentanyl substances 深圳海关工业品检测技术中心 2024-03-08 CN claimed
CN-117551203-A Preparation process of fentanyl monoclonal antibody 浙江工商大学 2024-02-13 CN claimed
CN-111257574-B Fluorescent immunity rapid detection card for rapid screening of fentanyl substances and preparation method 中检国研(北京)科技有限公司 2024-01-16 CN claimed
CN-116519657-A Surface-enhanced Raman spectrum substrate and preparation method and application thereof 中国人民解放军军事科学院军事医学研究院 2023-08-01 CN claimed
CN-113376277-B High-resolution mass spectrometry detection method for fentanyl drugs in health care products 西安海关技术中心 2023-03-17 CN claimed
US-20230015987-A1 METHOD FOR RAPID ON-SITE DETECTION OF FENTANYL ANALOGS USING A MINIATURE MASS SPECTROMETER CHINESE ACADEMY OF INSPECTION AND QUARANTINE (CN) 2023-01-19 US claimed
CN-113375997-B Method and product for detecting fentanyl compound 赛默飞世尔(上海)仪器有限公司 2022-02-18 CN claimed
CN-113375997-A Method and product for detecting fentanyl compound 赛默飞世尔(上海)仪器有限公司 2021-09-10 CN claimed
US-8710118-B2 Nano-pigment inkjet ink composition that has a low odor and is environmentally-friendly JETBEST CORPORATION (TW) 2014-04-29 US claimed
US-20130190421-A1 LOW ODOR ENVIRONMENTALLY-FRIENDLY NANO-PIGMENT INKJET INK COMPOSITION JETBEST CORPORATION (TW) 2013-07-25 US claimed
EP-2617779-A1 Low odor environmentally-friendly nano-pigment inkjet ink composition JETBEST Corporation (TW) 2013-07-24 EP claimed
EP-1406623-B1 SUBSTITUTED 1-PHENETHYLPIPERIDINE COMPOUNDS USED AS INTER ALIA ANALGESICS GRUENENTHAL GMBH (DE) 2007-12-12 EP claimed
US-20060100438-A1 Process of making fentanyl intermediates BOEHRINGER INGELHEIM CHEMICALS, INC. (US) 2006-05-11 US claimed
US-20040171640-A1 Substituted 1-phenethylpiperidine compounds used as inter alia analgesics GRUNENTHAL GMBH (DE) 2004-09-02 US claimed
EP-1406623-A1 SUBSTITUTED 1-PHENETHYLPIPERIDINE COMPOUNDS USED AS INTER ALIA ANALGESICS Grünenthal GmbH (DE) 2004-04-14 EP claimed
WO-2003004026-A1 SUBSTITUTED 1-PHENETHYLPIPERIDINE COMPOUNDS USED AS INTER ALIA ANALGESICS Grünenthal GmbH (DE) 2003-01-16 WO claimed
US-5106983-A Process of making carfentanil and related analgesics THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) 1992-04-21 US claimed
EP-0394039-A1 A method for preparing 4-Alkoxyalkyl-4-aminophenylpiperidines and derivatives thereof BOC, INC. (US) 1990-10-24 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040171640-A1 Substituted 1-phenethylpiperidine compounds used as inter alia analgesics PNMT, OPRK1, OPRM1 SLC6A3 565/4885SIGMAR1 30/4885HTR1A 11/4885
US-20060100438-A1 Process of making fentanyl intermediates OPRK1, OPRD1, OPRM1 SLC6A3 987/4885SIGMAR1 45/4885HTR1A 133/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.