Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | GLA | P06280 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22075534 | 0.95 | KDM4E (0.58) | KDM4EHPGDALDH1A1GLAKMT2A | |
| SCHEMBL15984890 | 0.82 | KDM4E (0.64) | KDM4EHPGDALDH1A1GLAKMT2A | |
| SCHEMBL18074001 | 0.81 | KDM4E (0.62) | KDM4EHPGDALDH1A1GLAKMT2A | |
| SCHEMBL18073970 | 0.79 | KDM4E (0.55) | KDM4EHPGDALDH1A1GLAKMT2A | |
| SCHEMBL15295521 | 0.71 | MCL1 (0.70) | KDM4EHPGDALDH1A1GLAKMT2A | |
| SCHEMBL31454860 | 0.71 | ALDH1A1 (0.58) | KDM4EHPGDALDH1A1GLAKMT2A | |
| SCHEMBL6559997 | 0.70 | GAA (0.71) | KDM4EHPGDALDH1A1GLAKMT2A | |
| SCHEMBL10144071 | 0.70 | KDM4E (0.60) | KDM4EHPGDALDH1A1KMT2AGAA | |
| SCHEMBL14756277 | 0.70 | ALDH1A1 (0.57) | KDM4EHPGDALDH1A1GLAKMT2A | |
| SCHEMBL31454895 | 0.70 | ALDH1A1 (0.48) | KDM4EHPGDALDH1A1GLAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200190050-A1 | LYSOSOMAL ACID LIPASE ASSAY | UNIVERSITY OF WASHINGTON (US) | 2020-06-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200190050-A1 | LYSOSOMAL ACID LIPASE ASSAY | LIPA, LPL, PNLIP | KDM4E 4408/4885HPGD 1589/4885ALDH1A1 1095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.