SCHEMBL22077249

SCHEMBL22077249

CC12C=CC(C)(C1)C(C(=O)O)=C2C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22077237 0.67 FFAR3 (0.38) FFAR3
SCHEMBL31296892 0.65 FFAR3 (0.41) FFAR3
SCHEMBL3670978 0.65
SCHEMBL3675735 0.64 PYGM (0.38) FFAR3
SCHEMBL31303951 0.60 FFAR3 (0.36) FFAR3
SCHEMBL31303950 0.60 FFAR3 (0.36) FFAR3
SCHEMBL8996032 0.60 TPMT (0.31)
Bicarbonate SCHEMBL2943876 0.58 FFAR3 (0.44) FFAR3
SCHEMBL6903585 0.58 ALDH1A1 (0.31)
SCHEMBL22077232 0.57 FFAR3 (0.39) FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3893889-B1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF TERNS INC (US) 2026-01-28 EP disclosed
US-20260001867-A1 THR BETA RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF TERNS PHARMACEUTICALS, INC. 2026-01-01 US disclosed
US-12459926-B2 THRβ receptor agonist compound and preparation method and use thereof Terns, Inc. (US) 2025-11-04 US disclosed
US-12365669-B2 THRβ receptor agonist compound and preparation method and use thereof Terns, Inc. (US) 2025-07-22 US disclosed
EP-4574821-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF Terns, Inc. (US) 2025-06-25 EP disclosed
US-12338232-B2 THRβ receptor agonist compound and preparation method and use thereof Terns, Inc. (US) 2025-06-24 US disclosed
US-20250179054-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF TERNS PHARMACEUTICALS, INC. 2025-06-05 US disclosed
US-20250179053-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF TERNS PHARMACEUTICALS, INC. 2025-06-05 US disclosed
EP-4529954-A2 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF Terns, Inc. (US) 2025-04-02 EP disclosed
US-20230278988-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF TERNS PHARMACEUTICALS, INC. 2023-09-07 US disclosed
EP-3893889-A1 THR? RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF Terns, Inc. (US) 2021-10-20 EP disclosed
US-11084802-B2 THRβ receptor agonist compound and preparation method and use thereof Terns, Inc. (US) 2021-08-10 US disclosed
US-11034676-B2 THRB receptor agonist compound and preparation method and use thereof Terns, Inc. (US) 2021-06-15 US disclosed
US-20200399249-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF TERNS PHARMACEUTICALS, INC. 2020-12-24 US disclosed
WO-2020123827-A1 THRΒ RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF Terns, Inc. (US) 2020-06-18 WO disclosed
US-20200190064-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF TERNS PHARMACEUTICALS, INC. 2020-06-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179054-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF THRB, THRA, TRHR FFAR3 97/4885
US-20260001867-A1 THR BETA RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF THRB, THRA, ADRB1 FFAR3 68/4885
US-20250179053-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF THRB, THRA, TRHR FFAR3 97/4885
US-20200190064-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF THRB, THRA, TRHR FFAR3 97/4885
US-20230278988-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF THRB, THRA, TRHR FFAR3 97/4885
US-12459926-B2 THRβ receptor agonist compound and preparation method and use thereof THRB, THRA, TRHR FFAR3 92/4885
US-12365669-B2 THRβ receptor agonist compound and preparation method and use thereof THRB, THRA, TRHR FFAR3 92/4885
US-11034676-B2 THRB receptor agonist compound and preparation method and use thereof THRB, THRA, TRHR FFAR3 97/4885
US-11084802-B2 THRβ receptor agonist compound and preparation method and use thereof THRB, THRA, TRHR FFAR3 92/4885
US-12338232-B2 THRβ receptor agonist compound and preparation method and use thereof THRB, THRA, TRHR FFAR3 92/4885
US-20200399249-A1 THRB RECEPTOR AGONIST COMPOUND AND PREPARATION METHOD AND USE THEREOF THRB, THRA, TRHR FFAR3 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.