Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.34 |
| ▸ | ACHE | P22303 | 5/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL2207805 | 0.86 | CA1 (0.39) | CA1CA2CA5ACA9ACHE | |
| SCHEMBL12434533 | 0.79 | ALDH1A1 (0.43) | CA1CA2LMNAMAPK1ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL9984533 | 0.77 | GPR3 (0.40) | GPR3CA1CA2CA9KCNH2 | |
| SCHEMBL27518342 | 0.77 | ALDH1A1 (0.42) | CA1CA2LMNAMAPK1ACHE | |
| Trifluoromethanesulfonic Acid SCHEMBL29720529 | 0.76 | LMNA (0.53) | GPR3CA1CA2CA5ACA9 | |
| Trifluoromethanesulfonic Acid SCHEMBL17477312 | 0.74 | APOBEC3A (0.54) | GPR3CA1CA2CA5ACA9 | |
| Trifluoromethanesulfonic Acid SCHEMBL1110767 | 0.74 | ALDH1A1 (0.37) | CA1CA2CA5ACA9CYP3A4 | |
| Trifluoromethanesulfonic Acid SCHEMBL2334847 | 0.73 | GPR3 (0.37) | GPR3CA1CA2CA9KCNH2 | |
| Trifluoromethanesulfonic Acid SCHEMBL8088040 | 0.69 | GPR3 (0.53) | GPR3CA1CA2CA5ACA9 | |
| Trifluoromethanesulfonic Acid SCHEMBL216802 | 0.67 | GPR3 (0.38) | GPR3CA1CA2KCNH2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7982038-B2 | Ligands | ASTRAZENECA AB (SE) | 2011-07-19 | — | — | US | disclosed |
| US-20070172420-A1 | Ligands | ASTRAZENECA AB (SE) | 2007-07-26 | — | — | US | disclosed |
| EP-1668016-A1 | LIGANDS | AstraZeneca AB (SE) | 2006-06-14 | — | — | EP | disclosed |
| WO-2005030778-A1 | LIGANDS | ASTRAZENECA AB (SE) | 2005-04-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070172420-A1 | Ligands | ADRA1A, GPR119, ADRB1 | GPR3 32/4885CA1 2404/4885CA2 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.