Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | MEP1B | Q16820 | 3/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30444058 | 0.84 | MEP1B (0.59) | MEP1BMRGPRX4NR1H4 | |
| SCHEMBL805218 | 0.84 | MEP1B (0.59) | MEP1BMRGPRX4NR1H4 | |
| SCHEMBL10131961 | 0.84 | NOS1 (0.51) | NOS1KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL4950108 | 0.83 | ALDH1A1 (0.48) | LOXL2CYP4F2CYP4A11MRGPRX4ALDH1A1 | |
| SCHEMBL2570385 | 0.82 | NOS1 (0.54) | NOS1LOXL2MEP1B | |
| SCHEMBL4168117 | 0.82 | NOS1 (0.46) | NOS1KDM4ECYP3A4MAPTPRMT6 | |
| SCHEMBL8277397 | 0.82 | SLC7A5 (0.59) | NOS1HDAC8HDAC6MRGPRX4NR1H4 | |
| SCHEMBL45633 | 0.81 | LOXL2 (0.68) | KDM4EMAPTLOXL2CYP4F2CYP4A11 | |
| SCHEMBL27326765 | 0.81 | L3MBTL1 (0.57) | NOS1KDM4ECYP3A4MAPTHDAC8 | |
| SCHEMBL27189401 | 0.81 | CYP1A2 (0.54) | MAPTMEP1BHDAC8HDAC6MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020113585-A1 | ACYLPHOSPHINE OXIDE COMPOUND AND PREPARATION METHOD THEREFOR | 安庆莱霆光电科技有限公司 | 2020-06-11 | — | — | WO | disclosed |