SCHEMBL22088326

SCHEMBL22088326

c1ccc2c(c1)oc1ccc(-c3c4ccccc4c(-c4ccc5oc6ccccc6c5c4)c4cc(-c5ccc6c(c5)oc5cccc(-c7c8ccccc8c(-c8cccc9oc%10ccccc%10c89)c8ccccc78)c56)ccc34)cc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.40
▸ MAPT P10636 4/20 0.40
▸ KMT2A Q03164 4/20 0.40
▸ NPC1 O15118 4/20 0.40
▸ RAB9A P51151 3/20 0.40
▸ AHR P35869 2/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ HPGD P15428 2/20 0.40
▸ SMN1; SMN2 Q16637 2/20 0.40
▸ HSP90AA1 P07900 1/20 0.39
▸ HSP90AB1 P08238 1/20 0.39
▸ ALOX5 P09917 1/20 0.38
▸ HCRTR1 O43613 1/20 0.37
▸ PLA2G2A P14555 2/20 0.36
▸ PLA2G4A P47712 2/20 0.36
▸ PLA2G10 O15496 1/20 0.36
▸ MMP12 P39900 1/20 0.36
▸ MMP13 P45452 1/20 0.36
▸ PRKDC P78527 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23426820 0.97 MAPT (0.41) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL23426536 0.97 MAPT (0.41) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL22088328 0.94 HCRTR1 (0.36) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL23057108 0.93 PLA2G2A (0.43) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL25624568 0.93 MMP12 (0.40) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL23427963 0.93 MEN1 (0.39) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL23428258 0.93 MEN1 (0.39) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL23427719 0.93 MEN1 (0.39) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL23426926 0.93 MEN1 (0.39) MEN1MAPTKMT2ANPC1RAB9A
SCHEMBL23427468 0.93 PLA2G2A (0.43) MEN1MAPTKMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE IDEMITSU KOSAN CO.,LTD. (JP) 2021-10-14 — — US disclosed
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2020-06-11 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210320251-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND ELECTRONIC APPLIANCE OLA1, TAS2R19, TMEM109 MEN1 2129/4885MAPT 2477/4885KMT2A 236/4885
US-20200181160-A1 COMPOUND, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE AHR, EMC2, NFE2L2 MEN1 1560/4885MAPT 2800/4885KMT2A 650/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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