Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | FDPS | P14324 | 7/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | ALPG | P10696 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8337291 | 0.70 | KDM4E (0.41) | MEN1KMT2AFDPSLMNASMN1; SMN2 | |
| SCHEMBL6448091 | 0.69 | CFTR (0.64) | HPGDMEN1KMT2AALDH1A1FDPS | |
| SCHEMBL22990157 | 0.67 | CA1 (0.45) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22990166 | 0.67 | CA1 (0.45) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| Benzylphosphonic Acid SCHEMBL44318 | 0.66 | HPGD (0.60) | HPGD | |
| SCHEMBL497159 | 0.66 | HPGD (0.60) | HPGDFDPS | |
| SCHEMBL29201710 | 0.65 | CFTR (0.64) | HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL9546859 | 0.65 | FDPS (0.66) | FDPSBTN3A1PDE3A | |
| Benzylphosphonic Acid SCHEMBL6442960 | 0.65 | ROCK2 (0.50) | HPGDSMN1; SMN2ALPLALPIALPG | |
| Benzylphosphonic Acid SCHEMBL6442957 | 0.65 | ROCK2 (0.50) | HPGDSMN1; SMN2ALPLALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3893872-A1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | Beta Pharma, Inc. (US) | 2021-10-20 | — | — | EP | disclosed |
| WO-2020124060-A1 | ORGANOPHOSPHORUS-SUBSTITUTED COMPOUNDS AS C-MET INHIBITORS AND THERAPEUTIC USES THEREOF | BETA PHARMA, INC. (US) | 2020-06-18 | — | — | WO | disclosed |