Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.60 |
| ▸ | YAP1 | P46937 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22097638 | 0.99 | ALDH1A1 (0.62) | ALDH1A1KDM4EYAP1HPGDALOX15 | |
| SCHEMBL27218058 | 0.87 | ALOX15 (0.56) | ALDH1A1KDM4EYAP1HPGDALOX15 | |
| SCHEMBL28999518 | 0.86 | KDM4E (0.58) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL5065680 | 0.84 | ALOX15 (0.77) | ALDH1A1KDM4EYAP1HPGDALOX15 | |
| SCHEMBL4583665 | 0.84 | YAP1 (0.55) | ALDH1A1KDM4EYAP1HPGDALOX15 | |
| SCHEMBL4250614 | 0.84 | KDM4E (0.70) | ALDH1A1KDM4EHPGDGAAMAPT | |
| SCHEMBL18594835 | 0.84 | KDM4E (0.70) | ALDH1A1KDM4EYAP1HPGDALOX15 | |
| SCHEMBL19335455 | 0.84 | KDM4E (0.70) | ALDH1A1KDM4EYAP1HPGDALOX15 | |
| SCHEMBL7065164 | 0.84 | KDM4E (0.70) | ALDH1A1KDM4EYAP1HPGDALOX15 | |
| SCHEMBL8833932 | 0.83 | YAP1 (0.62) | ALDH1A1KDM4EYAP1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11786890-B2 | Photo-redox titanium containing organic frameworks and methods of making and use thereof | FLORIDA STATE UNIVERSITY (US) | 2023-10-17 | — | — | US | disclosed |
| CN-110927137-B | Single-benzene-ring framework-based cell lipid drop fluorescence imaging probe and application thereof | 吉林大学 | 2021-04-27 | — | — | CN | disclosed |
| US-20200188896-A1 | PHOTO-REDOX TITANIUM CONTAINING ORGANIC FRAMEWORKS AND METHODS OF MAKING AND USE THEREOF | NATIONAL SCIENCE FOUNDATION | 2020-06-18 | — | — | US | disclosed |
| CN-110927137-A | Single-benzene-ring framework-based cell lipid drop fluorescence imaging probe and application thereof | 吉林大学 | 2020-03-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786890-B2 | Photo-redox titanium containing organic frameworks and methods of making and use thereof | PPOX, PPIF, CYBB | ALDH1A1 616/4885KDM4E 2531/4885YAP1 875/4885 |
| US-20200188896-A1 | PHOTO-REDOX TITANIUM CONTAINING ORGANIC FRAMEWORKS AND METHODS OF MAKING AND USE THEREOF | PPOX, PPIF, CYBB | ALDH1A1 616/4885KDM4E 2531/4885YAP1 875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.