Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22101713 | 0.87 | MAPT (0.34) | ALDH1A1RXFP1MAPTLMNAKDM4E | |
| SCHEMBL22393762 | 0.86 | BTK (0.31) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL22101917 | 0.86 | P2RX3 (0.31) | ALDH1A1L3MBTL1DPP4 | |
| SCHEMBL22101706 | 0.84 | HTR1A (0.32) | L3MBTL1MAPK14RXFP1MAPTLMNA | |
| SCHEMBL22101184 | 0.82 | CRHR1 (0.31) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL22101905 | 0.82 | PDE2A (0.31) | ALDH1A1L3MBTL1RXFP1MAPTKDM4E | |
| SCHEMBL22101709 | 0.77 | GRIN1 (0.32) | ALDH1A1RXFP1LMNAKDM4EHPGD | |
| SCHEMBL22393703 | 0.74 | SYK (0.37) | ALDH1A1KDM4E | |
| SCHEMBL23099580 | 0.72 | NPC1 (0.33) | ALDH1A1RXFP1LMNAHPGDGAA | |
| SCHEMBL22393702 | 0.70 | HCAR2 (0.32) | L3MBTL1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |