Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.30 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22393702 | 0.88 | HCAR2 (0.32) | METCYP1A2CYP3A4TSHRHSD17B10 | |
| SCHEMBL22101706 | 0.88 | HTR1A (0.32) | RXFP1KCNJ5KCNJ3ATML3MBTL1 | |
| SCHEMBL22101184 | 0.87 | CRHR1 (0.31) | ALDH1A1 | |
| SCHEMBL22393761 | 0.85 | MET (0.30) | MET | |
| SCHEMBL22101707 | 0.82 | ALDH1A1 (0.32) | RXFP1HSD17B10L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL22101713 | 0.80 | MAPT (0.34) | RXFP1TSHRKDM4EALDH1A1MAPT | |
| SCHEMBL22101709 | 0.79 | GRIN1 (0.32) | RXFP1TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL22101539 | 0.78 | FFAR4 (0.35) | PDE2AMETRXFP1CYP1A2CYP3A4 | |
| SCHEMBL22101906 | 0.77 | KDM4E (0.43) | RXFP1KDM4EALDH1A1MAPT | |
| SCHEMBL22393755 | 0.73 | P2RX7 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3666772-A1 | DIARYLTHIOHYDANTOIN COMPOUND AS ANDROGEN RECEPTOR ANTAGONIST | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-06-17 | — | — | EP | disclosed |