SCHEMBL221065

SCHEMBL221065

[c]1ccccccccn1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
NAPRT Q6XQN6 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL900 0.97
SCHEMBL5239897 0.97
SCHEMBL28807223 0.93
SCHEMBL28866168 0.93
SCHEMBL27610855 0.93
SCHEMBL4654442 0.93
SCHEMBL2961718 0.93
Hydrochloric Acid SCHEMBL8905669 0.93
SCHEMBL27777456 0.93
Bromide SCHEMBL8905455 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240215579-A1 USE OF ANTI-CLOTTING COMPOUNDS AS RODENTICIDES GULBA DIETRICH (DE) 2024-07-04 US disclosed
US-11702541-B2 Vesicular system and uses thereof AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2023-07-18 US disclosed
US-11678659-B2 Use as rodenticides of compounds that inhibit blood coagulation GULBA DIETRICH (DE) 2023-06-20 US disclosed
EP-3362436-B1 PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS UNIV ANTWERPEN (BE) 2021-06-30 EP disclosed
US-20190322864-A1 VESICULAR SYSTEM AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-10-24 US disclosed
US-10364350-B2 Vesicular system and uses thereof AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-07-30 US disclosed
US-10350172-B2 Stimuli-responsive interpolymer complex coated hollow silica vesicles AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-07-16 US disclosed
US-20190046455-A1 STIMULI-RESPONSIVE INTERPOLYMER COMPLEX COATED HOLLOW SILICA VESICLES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2019-02-14 US disclosed
EP-3362436-A1 PROCESS FOR THE CATALYTIC DIRECTED CLEAVAGE OF AMIDE-CONTAINING COMPOUNDS Universiteit Antwerpen (BE) 2018-08-22 EP disclosed
US-10022332-B2 Stimuli-responsive interpolymer complex coated hollow silica vesicles AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-07-17 US disclosed
WO-2011099932-A1 SMART POLYMERS FUNCTIONALIZED HOLLOW SILICA VESICLES AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-08-18 WO disclosed
US-20110124881-A1 PROCESS OF FORMING A PYRROLE COMPOUND NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2011-05-26 US disclosed
US-20100298576-A1 ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-11-25 US disclosed
WO-2010132029-A1 OCTAHYDRO BIQUINOLINE COMPOUND NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-11-18 WO disclosed
WO-2010123462-A1 VESICULAR SYSTEM AND USES THEREOF AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-10-28 WO disclosed
WO-2010090596-A1 HOLLOW SILICA PARTICLE WITH A POLYMER THEREON AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-08-12 WO disclosed
WO-2010044752-A1 AMPHIPHILIC POLYMERS AND NANOCRYSTALS COATED THEREWITH AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-04-22 WO disclosed
WO-2010027334-A1 NOVEL TRICYCLIC CHIRAL COMPOUNDS AND THEIR USE IN ASYMMETRIC CATALYSIS NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2010-03-11 WO disclosed
US-20090275065-A1 METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY NANYANG TECHNOLOGICAL UNIVERSITY 2009-11-05 US disclosed
CN-101547858-A Method for functionalizing carbon material AGENCY SCIENCE TECH & RES (SG) 2009-09-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110124881-A1 PROCESS OF FORMING A PYRROLE COMPOUND OXER1, OGDH, OPRD1 TSHR 1794/4885NAPRT 2362/4885TDP1 4779/4885
US-10350172-B2 Stimuli-responsive interpolymer complex coated hollow silica vesicles CD44, NSF, SUMO3 TSHR 3297/4885NAPRT 4234/4885TDP1 4723/4885
US-11678659-B2 Use as rodenticides of compounds that inhibit blood coagulation PLAT, F2R, PLAUR TSHR 438/4885NAPRT 639/4885TDP1 1391/4885
US-10022332-B2 Stimuli-responsive interpolymer complex coated hollow silica vesicles CD44, NSF, SUMO3 TSHR 3297/4885NAPRT 4234/4885TDP1 4723/4885
US-20090275065-A1 METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY LPO, MPO, GUSB TSHR 215/4885NAPRT 1290/4885TDP1 3318/4885
US-20190046455-A1 STIMULI-RESPONSIVE INTERPOLYMER COMPLEX COATED HOLLOW SILICA VESICLES CD44, NSF, SUMO3 TSHR 3297/4885NAPRT 4234/4885TDP1 4723/4885
US-20100298576-A1 ASYMMETRIC CYCLIZATION PROCESSES USING UNSATURATED NITRO COMPOUNDS NQO1, COASY, NOS2 TSHR 4207/4885NAPRT 98/4885TDP1 3674/4885
US-20240215579-A1 USE OF ANTI-CLOTTING COMPOUNDS AS RODENTICIDES PLG, F13B, F2 TSHR 3609/4885NAPRT 2030/4885TDP1 1460/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.