Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520268 | 0.72 | PARP1 (0.61) | PARP1 | |
| SCHEMBL7208524 | 0.71 | PNMT (0.53) | — | |
| SCHEMBL9529812 | 0.67 | DRD2 (0.47) | PARP1 | |
| SCHEMBL25775228 | 0.66 | CA1 (0.32) | — | |
| SCHEMBL4877761 | 0.63 | ASIC3 (0.60) | — | |
| SCHEMBL4868962 | 0.63 | PNMT (0.60) | — | |
| Hydrochloric Acid SCHEMBL11479781 | 0.62 | PNMT (0.58) | — | |
| SCHEMBL3365351 | 0.60 | DRD2 (0.59) | — | |
| SCHEMBL1200026 | 0.59 | PARP10 (0.64) | PARP1 | |
| SCHEMBL9756716 | 0.58 | DRD2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020123674-A1 | SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2020-06-18 | — | — | WO | disclosed |