SCHEMBL2211494

SCHEMBL2211494

Oc1ccc2nnsc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
NPC1 O15118 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
RAB9A P51151 1/20 0.46
HTT P42858 2/20 0.46
GAA P10253 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
BAZ1A Q9NRL2 4/20 0.44
NSD2 O96028 2/20 0.40
HSD17B1 P14061 1/20 0.40
HSD17B2 P37059 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2211155 0.83 THRB (0.50) ALDH1A1NPC1POLBMAPTRAB9A
SCHEMBL16782399 0.76 ALDH1A1 (0.44) ALDH1A1NPC1POLBMAPTRAB9A
SCHEMBL10630197 0.74 BAZ1A (0.47) ALDH1A1NPC1POLBMAPTRAB9A
SCHEMBL1292012 0.74 SMN1; SMN2 (0.46) ALDH1A1NPC1POLBMAPTRAB9A
SCHEMBL17538782 0.74 PRMT3 (0.48) ALDH1A1NPC1POLBMAPTRAB9A
SCHEMBL7576448 0.74 MAPT (0.46) ALDH1A1NPC1POLBMAPTRAB9A
SCHEMBL1291431 0.74 NPC1 (0.42) ALDH1A1NPC1POLBMAPTRAB9A
SCHEMBL507524 0.74 PRMT3 (0.45) ALDH1A1NPC1POLBMAPTRAB9A
SCHEMBL14582771 0.73 THRB (0.42) ALDH1A1NPC1POLBMAPTRAB9A
Phenol SCHEMBL3255895 0.71 GLA (0.44) ALDH1A1NPC1POLBMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1243178-A1 Method for protecting crops from parasitic weeds using benzothiazole derivatives KOGEL, KARL-HEINZ, Prof., Dr. (DE) 2002-09-25 EP claimed
US-6281168-B1 PROTECTING CEREAL CROPS AMERICAN CYANAMID CO. 2001-08-28 US claimed
EP-1021953-A1 Herbicidal compositions and method of safening herbicides using benzothiazole derivatives American Cyanamid Company (US) 2000-07-26 EP claimed
US-10787430-B2 Hemoglobin modifier compounds and uses thereof FRONTHERA U.S. PHARMACEUTICALS LLC (US) 2020-09-29 US disclosed
US-20190330181-A1 HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) 2019-10-31 US disclosed
WO-2017218960-A1 HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF FRONTHERA U.S. PHARMACEUTICALS LLC (US) 2017-12-21 WO disclosed
EP-1952918-B1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO (JP) 2013-05-22 EP disclosed
US-8440110-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG CO., LTD. (JP) 2013-05-14 US disclosed
US-20110175040-A1 METHOD FOR PRODUCING METAL PARTICLE DISPRESION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM TOYO INK MFG CO., LTD. (JP) 2011-07-21 US disclosed
US-7981327-B2 Method for producing metal particle dispersion, conductive ink using metal particle dispersion produced by such method, and conductive coating film TOYO INK MFG. CO. LTD. (JP) 2011-07-19 US disclosed
US-20090258202-A1 Method for Producing Metal Particle Dispersion, Conductive Ink Using Metal Particle Dispersion Produced by Such Method, and Conductive Coating Film GVP GESELLSCHAFT ZUR VERMARKTUNG DER PORENBRENNERTECHNIK MBH (DE) 2009-10-15 US disclosed
EP-1952918-A1 METHOD FOR PRODUCING METAL PARTICLE DISPERSION, CONDUCTIVE INK USING METAL PARTICLE DISPERSION PRODUCED BY SUCH METHOD, AND CONDUCTIVE COATING FILM Toyo Ink Mfg. Co., Ltd (JP) 2008-08-06 EP disclosed
EP-1243178-A1 Method for protecting crops from parasitic weeds using benzothiazole derivatives KOGEL, KARL-HEINZ, Prof., Dr. (DE) 2002-09-25 EP disclosed
US-6281168-B1 PROTECTING CEREAL CROPS AMERICAN CYANAMID CO. 2001-08-28 US disclosed
EP-1021953-A1 Herbicidal compositions and method of safening herbicides using benzothiazole derivatives American Cyanamid Company (US) 2000-07-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190330181-A1 HEMOGLOBIN MODIFIER COMPOUNDS AND USES THEREOF HBB, HBG1, HBG2 ALDH1A1 863/4885NPC1 2587/4885POLB 3664/4885
US-10787430-B2 Hemoglobin modifier compounds and uses thereof HBB, HBG1, HBG2 ALDH1A1 863/4885NPC1 2587/4885POLB 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.