SCHEMBL22117010

SCHEMBL22117010

Cc1cnc(OCc2ccccc2)cc1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GABRG2 P18507 2/20 0.48
▸ GABRB3 P28472 2/20 0.48
▸ GABRA5 P31644 2/20 0.48
▸ GABRA3 P34903 2/20 0.48
▸ GABRP O00591 1/20 0.48
▸ GABRD O14764 1/20 0.48
▸ GABRA1 P14867 1/20 0.48
▸ GABRB1 P18505 1/20 0.48
▸ GABRA2 P47869 1/20 0.48
▸ GABRB2 P47870 1/20 0.48
▸ GABRA4 P48169 1/20 0.48
▸ GABRE P78334 1/20 0.48
▸ GABRA6 Q16445 1/20 0.48
▸ GABRG1 Q8N1C3 1/20 0.48
▸ GABRG3 Q99928 1/20 0.48
▸ GABRQ Q9UN88 1/20 0.48
▸ NUDT1 P36639 1/20 0.48
▸ TSHR P16473 1/20 0.45
▸ FFAR1 O14842 4/20 0.43
▸ MAOB P27338 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31694526 0.83 PDE2A (0.49) MAOBL3MBTL1MAPTSMN1; SMN2RAB9A
SCHEMBL23301902 0.81 GABRA5 (0.48) GABRG2GABRB3GABRA5GABRA3GABRP
SCHEMBL29755761 0.81 GABRA5 (0.48) GABRG2GABRB3GABRA5GABRA3GABRP
SCHEMBL27983120 0.81 GABRP (0.48) GABRG2GABRB3GABRA5GABRA3GABRP
Hydrochloric Acid SCHEMBL15968325 0.79 GABRG2 (0.47) GABRG2GABRB3GABRA5GABRA3GABRP
SCHEMBL19466074 0.78 AOC3 (0.49) GABRG2GABRB3GABRA5GABRA3GABRP
SCHEMBL31251644 0.77 GABRG2 (0.48) GABRG2GABRB3GABRA5GABRA3GABRP
SCHEMBL22075603 0.77 GABRP (0.48) GABRG2GABRB3GABRA5GABRA3GABRP
SCHEMBL2470292 0.77 GABRA5 (0.48) GABRG2GABRB3GABRA5GABRA3GABRP
SCHEMBL17012052 0.77 GABRA5 (0.48) GABRG2GABRB3GABRA5GABRA3GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113242853-B Process for preparing 2-alkoxy-4-amino-5-methyl-pyridine and/or 2-alkoxy-4-alkylamino-5-methyl-pyridine 赛拓有限责任公司 2025-06-24 — — CN disclosed
US-12168644-B2 Process for preparing 2-alkoxy-4-amino-5-methyl-pyridines and/or 2-alkoxy-4-alkylamino-5-methyl-pyridines SALTIGO GMBH (DE) 2024-12-17 — — US disclosed
US-20220055992-A1 Process for preparing 2-alkoxy-4-amino-5-methyl-pyridines and/or 2-alkoxy-4-alkylamino-5-methyl-pyridines SALTIGO GMBH (DE) 2022-02-24 — — US disclosed
EP-3898589-A2 PROCESS FOR PREPARING 2-ALKOXY-4-AMINO-5-METHYL-PYRIDINES AND/OR 2-ALKOXY-4-ALKYLAMINO-5-METHYL-PYRIDINES Saltigo GmbH (DE) 2021-10-27 — — EP disclosed
CN-113242853-A Process for the preparation of 2-alkoxy-4-amino-5-methyl-pyridines and/or 2-alkoxy-4-alkylamino-5-methyl-pyridines 赛拓有限责任公司 2021-08-10 — — CN disclosed
WO-2020128020-A2 PROCESS FOR PREPARING 2-ALKOXY-4-AMINO-5-METHYL-PYRIDINES AND/OR 2-ALKOXY-4-ALKYLAMINO-5-METHYL-PYRIDINES SALTIGO GMBH (DE) 2020-06-25 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220055992-A1 Process for preparing 2-alkoxy-4-amino-5-methyl-pyridines and/or 2-alkoxy-4-alkylamino-5-methyl-pyridines ADH5, ADH1A, ADH1C GABRG2 410/4885GABRB3 629/4885GABRA5 58/4885
US-12168644-B2 Process for preparing 2-alkoxy-4-amino-5-methyl-pyridines and/or 2-alkoxy-4-alkylamino-5-methyl-pyridines ADH5, ADH1A, ADH1C GABRG2 410/4885GABRB3 629/4885GABRA5 58/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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