Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | CLPP | Q16740 | 2/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22119100 | 0.83 | AURKB (0.39) | CLPPALDH1A1SIGMAR1 | |
| SCHEMBL22118872 | 0.80 | TSHR (0.36) | KMT2AALDH1A1PNP | |
| SCHEMBL22119381 | 0.77 | RNASEH1 (0.34) | PNP | |
| SCHEMBL22118854 | 0.77 | RNASEH1 (0.34) | PNP | |
| SCHEMBL22118878 | 0.77 | SIGMAR1 (0.39) | CLPPALDH1A1SIGMAR1 | |
| SCHEMBL22119321 | 0.77 | PNP (0.40) | ALDH1A1PNP | |
| SCHEMBL22118853 | 0.76 | SLC6A2 (0.34) | KMT2AALDH1A1 | |
| SCHEMBL22119310 | 0.76 | RNASEH1 (0.34) | ALDH1A1PNP | |
| SCHEMBL22118859 | 0.75 | RNASEH1 (0.33) | PNP | |
| SCHEMBL22118888 | 0.75 | RNASEH1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897645-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | Acurx Pharmaceuticals, LLC (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132174-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | ACURX PHARMACEUTICALS, LLC (US) | 2020-06-25 | — | — | WO | disclosed |