SCHEMBL2212249

SCHEMBL2212249

CSc1ccc(O)cc1Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.56
BCL2 P10415 1/20 0.48
BCL2L1 Q07817 1/20 0.48
HSD17B3 P37058 1/20 0.43
KEAP1 Q14145 1/20 0.42
MEN1 O00255 1/20 0.41
CYP3A4 P08684 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 1/20 0.41
HSD17B10 Q99714 1/20 0.41
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
SLC6A3 Q01959 1/20 0.40
HSP90AA1 P07900 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3479885 0.83 LMNA (0.45) ALOX5KEAP1SLC6A2SLC6A4SLC6A3
SCHEMBL12174818 0.79 HTR2A (0.42) ALOX5BCL2BCL2L1HSP90AA1
SCHEMBL28840360 0.77 L3MBTL1 (0.47) BCL2BCL2L1MEN1KMT2ASLC6A2
SCHEMBL11764362 0.77 ALOX5 (0.74) ALOX5BCL2BCL2L1HSD17B3KEAP1
SCHEMBL3725690 0.77 ALOX5 (0.61) ALOX5BCL2BCL2L1HSD17B3KEAP1
SCHEMBL390179 0.76 ALOX5 (0.71) ALOX5BCL2BCL2L1HSD17B3KEAP1
SCHEMBL6292267 0.76 ALOX5 (0.71) ALOX5BCL2BCL2L1HSD17B3KEAP1
SCHEMBL5878543 0.76 HSD17B3 (0.40) ALOX5HSD17B3MEN1CYP3A4ALOX15
Butane SCHEMBL27663673 0.74 ALOX5 (0.62) ALOX5BCL2BCL2L1HSD17B3KEAP1
SCHEMBL10440731 0.73 MTNR1A (0.43) KMT2AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116774525-A Photosensitive resin composition, cured film and display device 武汉柔显科技股份有限公司 2023-09-19 CN disclosed
CN-114380998-B Alkali-soluble resin, positive photosensitive resin composition, cured film, and display device 武汉柔显科技股份有限公司 2023-08-11 CN disclosed
CN-114561008-B Alkali-soluble resin, positive photosensitive resin composition, cured film, and display device 武汉柔显科技股份有限公司 2023-08-11 CN disclosed
CN-105593246-A Colored composition, cured film, color filter, method for manufacturing color filter, solid-state imaging element, image display device, and compound FUJIFILM CORP 2016-05-18 CN disclosed
EP-2239301-B1 SILOXANE RESIN COMPOSITIONS TORAY INDUSTRIES (JP) 2016-04-27 EP disclosed
US-8389649-B2 Siloxane-based resin composition TORAY INDUSTRIES, INC. (JP) 2013-03-05 US disclosed
EP-1626309-B1 Hologram recording material, hologram recording method and holographic optical element FUJIFILM CORP (JP) 2011-07-27 EP disclosed
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION TORAY INDUSTRIES, INC. (JP) 2010-12-16 US disclosed
EP-2239301-A1 SILOXANE RESIN COMPOSITIONS Toray Industries, Inc. (JP) 2010-10-13 EP disclosed
EP-1626309-A2 Hologram recording material, hologram recording method and holographic optical element Fuji Photo Film Co., Ltd. (JP) 2006-02-15 EP disclosed
WO-2006013989-A1 CURABLE TRIAZINE COMPOSITION FOR ELECTRONIC COMPONENTS, PRODUCTION METHOD THEREFOR AND CURED PRODUCT THEREOF SHOWA DENKO K.K. (JP) 2006-02-09 WO disclosed
US-20050214650-A1 Hologram recording material, hologram recording method, optical recording medium, three-dimensional display hologram and holographic optical element FUJI PHOTO FILM CO., LTD. 2005-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100316953-A1 SILOXANE-BASED RESIN COMPOSITION ICAM1, ESD, CAD ALOX5 100/4885BCL2 4306/4885BCL2L1 4085/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.