Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.36 |
| ▸ | USP7 | Q93009 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.32 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.32 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22140338 | 0.88 | MAPT (0.41) | PGRMAPTCASP1AURKATTK | |
| SCHEMBL25566319 | 0.79 | MAPT (0.34) | PGRMAPTCASP1AURKATTK | |
| SCHEMBL25910716 | 0.78 | ALDH1A1 (0.48) | MAPTCASP1AURKATTKAURKB | |
| SCHEMBL24131086 | 0.76 | PIK3CD (0.33) | MAPTCASP1PIK3CDPIK3CA | |
| SCHEMBL22140342 | 0.76 | PGR (0.38) | PGRALOX5APFEN1USP7KDM4E | |
| SCHEMBL22140350 | 0.76 | FEN1 (0.36) | PGRALOX5APFEN1PIK3CDMAP4K4 | |
| SCHEMBL25566381 | 0.73 | PIK3CD (0.32) | PIK3CDPIK3CA | |
| SCHEMBL24852675 | 0.72 | NOS3 (0.42) | MAPTTDP1KDM4EALDH1A1GAA | |
| SCHEMBL30788039 | 0.72 | NOS3 (0.42) | MAPTTDP1KDM4EALDH1A1GAA | |
| SCHEMBL24852699 | 0.70 | PGR (0.36) | PGRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230365503-A1 | CRYSTAL FORM OF PYRIDINYLPHENYL COMPOUND AND PREPARATION METHOD THEREFOR | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| US-20230365503-A1 | CRYSTAL FORM OF PYRIDINYLPHENYL COMPOUND AND PREPARATION METHOD THEREFOR | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2023-11-16 | — | — | US | disclosed |
| EP-4219451-A1 | CRYSTAL FORM OF PYRIDINYLPHENYL COMPOUND AND PREPARATION METHOD THEREFOR | Zhuhai United Laboratories Co., Ltd. (CN) | 2023-08-02 | — | — | EP | disclosed |
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ZHUHAI UNITED LABORATORIES CO., LTD. (CN) | 2022-04-28 | — | — | US | disclosed |
| EP-3901138-A1 | COMPOUND FOR USE IN RETINAL DISEASES | Medshine Discovery Inc. (CN) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020125659-A1 | COMPOUND FOR USE IN RETINAL DISEASES | 南京明德新药研发有限公司 | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365503-A1 | CRYSTAL FORM OF PYRIDINYLPHENYL COMPOUND AND PREPARATION METHOD THEREFOR | FARS2, CYP4F11, CYP4F8 | PGR 1020/4885MAPT 514/4885CASP1 281/4885 |
| US-20220127243-A1 | COMPOUND FOR USE IN RETINAL DISEASES | ALDH1A2, ALDH1A3, NR2E3 | PGR 4341/4885MAPT 231/4885CASP1 4338/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.