Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19595940 | 0.86 | CDK9 (0.40) | CDK9DYRK1ADYRK2KMT2AMEN1 | |
| SCHEMBL22356518 | 0.82 | PLA2G2A (0.38) | CDK9DYRK1ADYRK2KDM4EMAPT | |
| SCHEMBL24961104 | 0.80 | PLA2G2A (0.38) | CDK9DYRK1ADYRK2MAPTALDH1A1 | |
| SCHEMBL24718901 | 0.80 | PLA2G2A (0.36) | CDK9DYRK1ADYRK2MAOBKDM4E | |
| SCHEMBL20975804 | 0.80 | ALDH1A1 (0.38) | KMT2AKDM4ESMN1; SMN2MAPTMAPK1 | |
| SCHEMBL22063393 | 0.80 | L3MBTL1 (0.36) | CDK9DYRK1ADYRK2MAOBKMT2A | |
| SCHEMBL22213009 | 0.77 | SMN1; SMN2 (0.41) | CDK9DYRK1ADYRK2KMT2AMEN1 | |
| SCHEMBL22766711 | 0.77 | PLA2G2A (0.34) | CDK9DYRK1ADYRK2MAOBL3MBTL1 | |
| SCHEMBL22766735 | 0.76 | MAOA (0.36) | CDK9DYRK1ADYRK2MAOBKMT2A | |
| SCHEMBL20071932 | 0.75 | L3MBTL1 (0.36) | CDK9DYRK1ADYRK2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3670510-A2 | BENZO[B]NAPHTHO[2,3-D]FURANYL- OR BENZO[B]NAPHTHO[2,3-D]THIOPHENYL-TRIAZINE COMPOUNDS FOR ORGANIC ELECTRONIC ELEMENTS | Duk San Neolux Co., Ltd. (KR) | 2020-06-24 | — | — | EP | disclosed |