Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALPG | P10696 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | NQO1 | P15559 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24515495 | 0.87 | MAOB (0.37) | ALDH1A1SMN1; SMN2MAPTNPC1L3MBTL1 | |
| SCHEMBL22213009 | 0.84 | SMN1; SMN2 (0.41) | ALDH1A1SMN1; SMN2MAPTALPGNPC1 | |
| SCHEMBL21201756 | 0.81 | MAPT (0.42) | ALDH1A1SMN1; SMN2KCNH2LMNAMAPT | |
| SCHEMBL20019274 | 0.80 | L3MBTL1 (0.54) | ALDH1A1SMN1; SMN2KCNH2LMNAMAPT | |
| SCHEMBL22147289 | 0.80 | CDK9 (0.40) | ALDH1A1SMN1; SMN2KCNH2LMNAMAPT | |
| SCHEMBL19595940 | 0.80 | CDK9 (0.40) | ALDH1A1SMN1; SMN2KCNH2LMNAMAPT | |
| SCHEMBL23430413 | 0.79 | MAPT (0.41) | ALDH1A1SMN1; SMN2LMNAMAPTALPG | |
| SCHEMBL22908094 | 0.78 | MAOA (0.47) | ALDH1A1SMN1; SMN2LMNAMAPTNPC1 | |
| SCHEMBL718538 | 0.76 | ALPG (0.51) | ALDH1A1SMN1; SMN2KCNH2LMNAMAPT | |
| SCHEMBL22356518 | 0.76 | PLA2G2A (0.38) | ALDH1A1MAPTL3MBTL1KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10283720-B2 | Compound, composition and organic light-emitting device | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2019-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10283720-B2 | Compound, composition and organic light-emitting device | XRN2, CRY1, GALR1 | ALDH1A1 446/4885SMN1; SMN2 2563/4885KCNH2 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.