Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.76 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.76 |
| ▸ | ACHE | P22303 | 2/20 | 0.71 |
| ▸ | HTR1A | P08908 | 6/20 | 0.68 |
| ▸ | HTR2A | P28223 | 5/20 | 0.68 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.68 |
| ▸ | HTR2C | P28335 | 2/20 | 0.68 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.68 |
| ▸ | HRH1 | P35367 | 2/20 | 0.68 |
| ▸ | DRD3 | P35462 | 2/20 | 0.68 |
| ▸ | HTR6 | P50406 | 2/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL718326 | 0.87 | DRD2 (0.69) | DRD2SLC6A4ACHEHTR1AHTR2A | |
| SCHEMBL27543378 | 0.87 | DRD2 (0.83) | DRD2SLC6A4ACHEHTR1AHTR2A | |
| SCHEMBL27445739 | 0.87 | DRD2 (0.83) | DRD2SLC6A4ACHEHTR1AHTR2A | |
| SCHEMBL8788175 | 0.86 | HTR1A (0.77) | DRD2SLC6A4ACHEHTR1AHTR2A | |
| SCHEMBL1545611 | 0.86 | ACHE (0.93) | DRD2SLC6A4ACHEHTR1AHTR2A | |
| SCHEMBL7356255 | 0.86 | DRD2 (0.77) | DRD2SLC6A4ACHEHTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL7775068 | 0.86 | HTR1A (0.76) | DRD2SLC6A4ACHEHTR1AHTR2A | |
| SCHEMBL1545461 | 0.85 | HTR1A (0.76) | DRD2HTR1AHTR2AHRH3HTR2C | |
| SCHEMBL7355139 | 0.85 | ACHE (0.68) | DRD2SLC6A4ACHEHTR1AHTR2A | |
| Alcohol SCHEMBL142048 | 0.85 | DRD2 (0.66) | DRD2SLC6A4ACHEHTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020125580-A1 | IMPURITIES OF AMIDE DERIVATIVES AND USE THEREOF | 江苏恩华药业股份有限公司 | 2020-06-25 | — | — | WO | disclosed |