Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 5/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | JAK3 | P52333 | 8/20 | 0.41 |
| ▸ | JAK2 | O60674 | 7/20 | 0.41 |
| ▸ | JAK1 | P23458 | 7/20 | 0.41 |
| ▸ | TYK2 | P29597 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121278 | 0.95 | CHEK2 (0.52) | CHEK2GPR119RORCJAK3JAK2 | |
| SCHEMBL22150565 | 0.91 | CHEK2 (0.48) | CHEK2GPR119RORCJAK3JAK2 | |
| SCHEMBL22121213 | 0.87 | RORC (0.53) | CHEK2GPR119RORCKMT2A | |
| SCHEMBL22135094 | 0.80 | STING1 (0.66) | — | |
| SCHEMBL21496906 | 0.77 | P2RX3 (0.48) | CHEK2RORCKMT2APTGER4 | |
| SCHEMBL22121292 | 0.76 | JAK2 (0.45) | JAK3JAK2JAK1TYK2KMT2A | |
| SCHEMBL22857833 | 0.75 | CHEK2 (0.45) | CHEK2GPR119 | |
| SCHEMBL22150045 | 0.74 | GPR119 (0.46) | CHEK2GPR119 | |
| SCHEMBL22121609 | 0.74 | JAK2 (0.51) | JAK3JAK2JAK1TYK2KMT2A | |
| SCHEMBL21310756 | 0.73 | PDE4B (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |