Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2947619 | 0.95 | LPL (0.48) | LPLLIPGS1PR1THRATHRB | |
| SCHEMBL18704586 | 0.94 | LPL (0.42) | LPLLIPGS1PR1THRATHRB | |
| SCHEMBL2146769 | 0.89 | CTSS (0.42) | LPLLIPGS1PR1THRATHRB | |
| SCHEMBL16499739 | 0.88 | RXRA (0.42) | LPLLIPGCTSSCTSKPDE3B | |
| SCHEMBL6901029 | 0.87 | LPL (0.36) | LPLLIPGS1PR1HIF1AAAK1 | |
| SCHEMBL2146382 | 0.87 | S1PR1 (0.42) | LPLLIPGS1PR1CTSSCTSK | |
| SCHEMBL28553153 | 0.86 | THRA (0.43) | LPLLIPGTHRATHRBCTSS | |
| SCHEMBL6897919 | 0.85 | KDM4E (0.41) | LPLLIPGS1PR1HIF1AAAK1 | |
| SCHEMBL16335131 | 0.83 | PDK2 (0.40) | S1PR1THRATHRBHIF1AAAK1 | |
| SCHEMBL20361068 | 0.83 | LPL (0.45) | LPLLIPGS1PR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3013796-B9 | BIARYL DERIVATIVES AS GPR120 AGONISTS | LG CHEMICAL LTD (KR) | 2020-07-01 | — | — | EP | disclosed |