Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 2/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | F11 | P03951 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.34 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18704586 | 0.86 | LPL (0.42) | AAK1DGAT1LPLLIPGF2 | |
| SCHEMBL2146787 | 0.85 | F2 (0.41) | KDM4EALDH1A1GAAAAK1DGAT1 | |
| SCHEMBL22150433 | 0.85 | LPL (0.45) | AAK1DGAT1LPLLIPGHIF1A | |
| SCHEMBL6901029 | 0.85 | LPL (0.36) | AAK1DGAT1LPLLIPGF2 | |
| SCHEMBL2146382 | 0.85 | S1PR1 (0.42) | AAK1DGAT1LPLLIPGS1PR1 | |
| SCHEMBL2146769 | 0.84 | CTSS (0.42) | KDM4EALDH1A1AAK1DGAT1LPL | |
| SCHEMBL16499739 | 0.83 | RXRA (0.42) | AAK1LPLLIPGF2F11 | |
| SCHEMBL2947619 | 0.83 | LPL (0.48) | LPLLIPGS1PR1S1PR4 | |
| SCHEMBL28553153 | 0.82 | THRA (0.43) | KDM4EALDH1A1AAK1LPLLIPG | |
| SCHEMBL2146802 | 0.82 | AAK1 (0.49) | AAK1DGAT1LMNAF2F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011086125-A1 | 1H-[1,2,3]TRIAZOLO[4,5-c]PYRIDINE-4-CARBONITRILE DERIVATIVES | N.V. ORGANON (NL) | 2011-07-21 | — | — | WO | disclosed |