Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | LIPE | Q05469 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6731066 | 0.79 | SIGMAR1 (0.43) | HRH3HPGDLIPERAB9APOLB | |
| SCHEMBL7501330 | 0.75 | LTA4H (0.45) | HRH3ALDH1A1LTA4HPTGS2KMT2A | |
| SCHEMBL325608 | 0.74 | SIGMAR1 (0.42) | HRH3LIPEPOLBLTA4HPTGS2 | |
| SCHEMBL9534090 | 0.72 | CYP2D6 (0.43) | HRH3ALDH1A1KDM4EKMT2AMEN1 | |
| SCHEMBL7502501 | 0.71 | LTA4H (0.50) | HRH3RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL7500095 | 0.69 | HPGD (0.50) | HPGDRAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL11083943 | 0.68 | KMT2A (0.46) | HPGDLIPERAB9APOLBMAPT | |
| SCHEMBL1002275 | 0.68 | HTR7 (0.42) | HRH3POLBLTA4HPTGS2KMT2A | |
| SCHEMBL992649 | 0.68 | HRH3 (0.40) | HRH3SIGMAR1TP53 | |
| SCHEMBL1002277 | 0.68 | HTR7 (0.42) | HRH3POLBLTA4HPTGS2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178079-A1 | GUANIDINE COMPOUNDS AS ANESTHETICS AND FOR TREATMENT OF NERVOUS SYSTEM DISORDERS | TAKTIX CORPORATION | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178079-A1 | GUANIDINE COMPOUNDS AS ANESTHETICS AND FOR TREATMENT OF NERVOUS SYSTEM DISORDERS | CACNA1E, GRIA4, GRIA3 | HRH3 440/4885HPGD 2197/4885LIPE 4809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.