Propionic Acid

Propionic Acid

SCHEMBL22160486

CCC(=O)O.COCc1c(F)c(F)c(CO)c(F)c1F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.37
GCGR P47871 1/20 0.33
IMPDH2 P12268 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL22129233 0.89 PRKCE (0.36) GCGRIMPDH2
Propionic Acid SCHEMBL28282690 0.86 FFAR3 (0.50) FFAR3IMPDH2
SCHEMBL359266 0.86 GCGR (0.39) GCGR
Propionic Acid SCHEMBL28282750 0.81 CA2 (0.41) FFAR3IMPDH2
Alcohol SCHEMBL22160482 0.76 CYP1A2 (0.37) GCGR
SCHEMBL22129230 0.76 POLB (0.40) IMPDH2
SCHEMBL22160485 0.76 CYP1A2 (0.36)
SCHEMBL22129223 0.75 MMP1 (0.36) IMPDH2
SCHEMBL19688655 0.75 GCGR (0.36) GCGR
SCHEMBL9766130 0.75 RECQL (0.38) IMPDH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10745334-B2 Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) 2020-08-18 US disclosed
US-20200207693-A1 METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL ZHEJIANG ZHONGXIN FLUORIDE MAT CO LTD (CN) 2020-07-02 US disclosed
CN-109438234-B Synthetic method of 2,3,5, 6-tetrafluoro-4-methoxymethyl benzyl alcohol 浙江中欣氟材股份有限公司 2020-04-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10745334-B2 Method for synthesizing 2,3,5,6-tetrafluoro-4-methoxymethyl benzyl alcohol TET2, TH, ALKBH2 FFAR3 1336/4885GCGR 4661/4885IMPDH2 1256/4885
US-20200207693-A1 METHOD FOR SYNTHESIZING 2,3,5,6-TETRAFLUORO-4-METHOXYMETHYL BENZYL ALCOHOL TH, ALKBH2, ALKBH3 FFAR3 1625/4885GCGR 4714/4885IMPDH2 1027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.