Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214686 | 0.94 | KDM4E (0.45) | HSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL2216828 | 0.88 | PGR (0.46) | KDM4EHPGDALDH1A1CNR2PSEN1 | |
| SCHEMBL29217020 | 0.88 | KDM4E (0.46) | HSD17B10KDM4EHPGDALDH1A1 | |
| SCHEMBL2215730 | 0.87 | ALDH1A1 (0.43) | KDM4EHPGDALDH1A1CNR2PSEN1 | |
| SCHEMBL2218201 | 0.84 | AGTR1 (0.47) | HSD17B10KDM4EAGTR1 | |
| SCHEMBL2214911 | 0.82 | ALDH1A1 (0.44) | KDM4EHPGDALDH1A1 | |
| SCHEMBL2214021 | 0.81 | PLA2G2A (0.43) | HPGDALDH1A1CNR2PSEN1PSEN2 | |
| SCHEMBL2214020 | 0.80 | CNR2 (0.52) | HSD17B10KDM4EHPGDALDH1A1CNR2 | |
| SCHEMBL2218129 | 0.80 | PGR (0.47) | HPGDALDH1A1CNR2PSEN1PSEN2 | |
| SCHEMBL2212262 | 0.79 | PDE4A (0.48) | HSD17B10KDM4EHPGDALDH1A1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1634881-B1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD (CN) | 2011-07-27 | — | — | EP | claimed |