Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 1.00 |
| ▸ | GAA | P10253 | 2/20 | 1.00 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.84 |
| ▸ | TUBB | P07437 | 3/20 | 0.84 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.84 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.84 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.84 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.84 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.84 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.84 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.84 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.84 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.84 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.84 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.84 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.84 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.84 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.81 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27969069 | 0.92 | MAPT (0.85) | MAPTKDM4EGAATUBB4ATUBB | |
| SCHEMBL7921852 | 0.91 | TUBB4A (1.00) | MAPTKDM4EGAATUBB4ATUBB | |
| SCHEMBL28652987 | 0.91 | KDM4E (0.84) | MAPTKDM4EGAATUBB4ATUBB | |
| SCHEMBL1764666 | 0.90 | KDM4E (0.82) | MAPTKDM4EGAATUBB4ATUBB | |
| SCHEMBL31511429 | 0.90 | KDM4E (0.82) | MAPTKDM4EGAATUBB4ATUBB | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL31621487 | 0.90 | ABCG2 (1.00) | MAPTKDM4EGAATUBB4ATUBB | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL1764676 | 0.90 | ABCG2 (1.00) | MAPTKDM4EGAATUBB4ATUBB | |
| 3,5,6,7,8,3',4'-Heptamethoxyflavone SCHEMBL29467229 | 0.90 | ABCG2 (1.00) | MAPTKDM4EGAATUBB4ATUBB | |
| Natsudaidai SCHEMBL890712 | 0.86 | ABCG2 (0.79) | MAPTKDM4EGAATUBB4ATUBB | |
| Natsudaidai SCHEMBL31237778 | 0.86 | ABCG2 (0.79) | MAPTKDM4EGAATUBB4ATUBB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260115294-A1 | DERIVATIVES OF 5-HYDROXYLATED POLYMETHOXYFLAVONES WITH ENHANCED BIOAVAILABILITY FOR ORAL DELIVERY AND COMPOSITIONS THEREOF | DEEPSENSE BIOTECHNOLOGIES INC (US) | 2026-04-30 | — | — | US | claimed |
| CN-112691052-A | Pure natural high-stability polymethoxylated flavone nano-emulsion and preparation and application thereof | 杭州诺莘科技有限责任公司 | 2021-04-23 | — | — | CN | claimed |
| US-10682332-B2 | Method for treating melanoma | Huanggang normal university (CN) | 2020-06-16 | — | — | US | claimed |
| US-20190046498-A1 | METHOD FOR TREATING MELANOMA | HENAN UNIVERSITY (CN) | 2019-02-14 | — | — | US | claimed |
| WO-2018125950-A1 | A COMBINATION THERAPY FOR TREATING CANCER | Huanggang normal university (CN) | 2018-07-05 | — | — | WO | claimed |
| US-9763910-B1 | Combination therapy for treating cancer | Huanggang normal university (CN) | 2017-09-19 | — | — | US | claimed |
| US-9669003-B2 | Use of flavone and flavanone derivatives in preparation of sedative and hypnotic drugs | JIN YONGRI (CN) | 2017-06-06 | — | — | US | claimed |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | JIN YONGRI (CN) | 2015-07-16 | — | — | US | claimed |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | WLLGEN, INC. (US) | 2014-02-06 | — | — | US | claimed |
| US-20110123653-A1 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2011-05-26 | — | — | US | claimed |
| EP-1883300-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | Rutgers, The State University of New Jersey (US) | 2008-02-06 | — | — | EP | claimed |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | WELLGEN, INC. | 2007-11-29 | — | — | US | claimed |
| WO-2007109071-A2 | HYDROXYLATED POLYMETHOXYFLAVONE COMPOSITIONS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-09-27 | — | — | WO | claimed |
| WO-2007083263-A1 | PROCESS TO PREPARE FLAVONES | FIRMENICH SA (CH) | 2007-07-26 | — | — | WO | claimed |
| US-20070088078-A1 | Methods for managing adipocyte fat accumulation | WELLGEN, INC. | 2007-04-19 | — | — | US | claimed |
| US-7201928-B1 | Extracts of orange peel for prevention and treatment of cancer | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2007-04-10 | — | — | US | claimed |
| WO-2007024982-A2 | METHODS FOR MANAGING ADIPOCYTE FAT ACCUMULATION | WELLGEN, INC. (US) | 2007-03-01 | — | — | WO | claimed |
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY | 2007-02-22 | — | — | US | claimed |
| WO-2006127996-A2 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2006-11-30 | — | — | WO | claimed |
| US-6184246-B1 | Inhibition of cytokine production by polymethoxylated flavones | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2001-02-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070042972-A1 | Compositions and methods for optimizing exercise recovery | GYS1, PYGM, PRDX5 | MAPT 4515/4885KDM4E 121/4885GAA 3638/4885 |
| US-20070088078-A1 | Methods for managing adipocyte fat accumulation | FABP4, PLIN5, PLIN3 | MAPT 3872/4885KDM4E 248/4885GAA 1593/4885 |
| US-20260115294-A1 | DERIVATIVES OF 5-HYDROXYLATED POLYMETHOXYFLAVONES WITH ENHANCED BIOAVAILABILITY FOR ORAL DELIVERY AND COMPOSITIONS THEREOF | PLIN3, PNLIP, FABP2 | MAPT 4716/4885KDM4E 2460/4885GAA 540/4885 |
| US-20070275106-A1 | Hydroxylated polymethoxyflavone compositions | PLIN5, FANCF, COXFA4 | MAPT 4329/4885KDM4E 1277/4885GAA 1679/4885 |
| US-20110123653-A1 | COMPOSITIONS AND METHODS FOR OPTIMIZING EXERCISE RECOVERY | GYS1, PYGM, PRDX5 | MAPT 4515/4885KDM4E 121/4885GAA 3638/4885 |
| US-20150196529-A1 | USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS | CYP2D6, GATAD2A, CYP3A43 | MAPT 1508/4885KDM4E 437/4885GAA 2289/4885 |
| US-20140039044-A1 | Hydroxylated Polymethoxyflavone Compositions | PLIN5, FANCF, COXFA4 | MAPT 4329/4885KDM4E 1277/4885GAA 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.