Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539191 | 0.84 | CTRL (0.32) | SMYD3NPC1TP53HPGDTSHR | |
| SCHEMBL22167426 | 0.81 | PSMB2 (0.30) | — | |
| SCHEMBL22167414 | 0.78 | KIFC1 (0.33) | — | |
| SCHEMBL17532371 | 0.78 | KIFC1 (0.33) | — | |
| SCHEMBL28547699 | 0.78 | CASP1 (0.38) | SMYD3NPC1TP53HPGDTSHR | |
| SCHEMBL17539147 | 0.77 | PYGL (0.32) | SMYD3NPC1TP53HPGDTSHR | |
| SCHEMBL17532348 | 0.76 | F2 (0.32) | SMYD3NPC1TP53HPGDTSHR | |
| SCHEMBL22167192 | 0.75 | — | — | |
| SCHEMBL17492904 | 0.75 | PYGL (0.31) | NPC1TP53HPGDTSHRRAB9A | |
| SCHEMBL22167427 | 0.75 | PYGL (0.31) | NPC1TP53HPGDTSHRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172199-B1 | PYRIMIDINE DERIVATIVES AS GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-07-01 | — | — | EP | disclosed |