SCHEMBL22171871

SCHEMBL22171871

c1ccc(-c2cc(-c3ccccc3)nc(-c3oc4cccc5c4c3-c3ccccc3-c3ccccc3-5)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 10/20 0.40
▸ KMT2A Q03164 10/20 0.40
▸ MAPT P10636 8/20 0.40
▸ ALDH1A1 P00352 5/20 0.40
▸ HPGD P15428 5/20 0.40
▸ LMNA P02545 3/20 0.40
▸ KDM4E B2RXH2 2/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.39
▸ ADORA1 P30542 3/20 0.39
▸ ADORA2A P29274 2/20 0.39
▸ L3MBTL1 Q9Y468 2/20 0.39
▸ NTSR1 P30989 1/20 0.38
▸ TDP1 Q9NUW8 2/20 0.37
▸ CYP1A2 P05177 2/20 0.37
▸ CYP2C9 P11712 2/20 0.37
▸ CYP2C19 P33261 2/20 0.37
▸ GLA P06280 1/20 0.37
▸ MAPK10 P53779 1/20 0.37
▸ AGTR1 P30556 2/20 0.36
▸ TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22171878 0.88 L3MBTL1 (0.38) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21366604 0.84 MEN1 (0.48) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22171897 0.81 MEN1 (0.35) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22171993 0.81 MEN1 (0.44) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22171893 0.81 PLA2G2A (0.37) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22171877 0.80 MEN1 (0.45) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL21366607 0.78 MEN1 (0.36) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL22172081 0.77 HPGD (0.39) MEN1KMT2AMAPTALDH1A1HPGD
SCHEMBL20863693 0.76 NTRK1 (0.36) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL22171894 0.76 L3MBTL1 (0.38) MEN1KMT2AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 — — US disclosed
US-11387417-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-07-12 — — US disclosed
US-20210043848-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-02-11 — — US disclosed
US-20210028369-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-28 — — US disclosed
US-20200235307-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2020-07-23 — — US disclosed
US-20200207713-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 — — US disclosed
US-20200207712-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387417-B2 Organic electroluminescent device L3MBTL4, SLC39A14, CTCF MEN1 3528/4885KMT2A 2851/4885MAPT 1021/4885
US-20210028369-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LIMS1, TERT, TELO2 MEN1 2420/4885KMT2A 3640/4885MAPT 1011/4885
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, SOD1, TELO2 MEN1 2689/4885KMT2A 1846/4885MAPT 1027/4885
US-20210043848-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LIMS1, TERT, TELO2 MEN1 2167/4885KMT2A 3716/4885MAPT 507/4885
US-20200207713-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 MEN1 2689/4885KMT2A 1846/4885MAPT 1027/4885
US-20200207712-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 MEN1 2689/4885KMT2A 1846/4885MAPT 1027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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