SCHEMBL22171894

SCHEMBL22171894

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-c4oc5cccc6c5c4-c4ccccc4-c4ccccc4-6)c4ccccc34)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 5/20 0.38
▸ TSHR P16473 3/20 0.38
▸ ALDH1A1 P00352 3/20 0.38
▸ MAPT P10636 3/20 0.38
▸ KDM4E B2RXH2 3/20 0.38
▸ HPGD P15428 2/20 0.38
▸ TDP1 Q9NUW8 2/20 0.38
▸ TP53 P04637 2/20 0.38
▸ MAPK1 P28482 2/20 0.38
▸ NFKB1 P19838 1/20 0.38
▸ NFKB2 Q00653 1/20 0.38
▸ RELA Q04206 1/20 0.38
▸ ATM Q13315 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ ADORA3 P0DMS8 2/20 0.35
▸ ALOX15 P16050 2/20 0.35
▸ NTRK1 P04629 1/20 0.35
▸ PLK3 Q9H4B4 1/20 0.35
▸ ADORA2A P29274 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22171878 0.87 L3MBTL1 (0.38) L3MBTL1TSHRALDH1A1MAPTKDM4E
SCHEMBL22171893 0.86 PLA2G2A (0.37) L3MBTL1TSHRALDH1A1MAPTKDM4E
SCHEMBL22171897 0.83 MEN1 (0.35) L3MBTL1TSHRALDH1A1MAPTKDM4E
SCHEMBL23821351 0.81 GPR55 (0.40) L3MBTL1TSHRALDH1A1MAPTKDM4E
SCHEMBL23385057 0.80 MAPT (0.41) L3MBTL1TSHRALDH1A1MAPTKDM4E
SCHEMBL21366605 0.80 TSHR (0.37) L3MBTL1TSHRALDH1A1MAPTKDM4E
SCHEMBL24930610 0.80 MAPT (0.38) L3MBTL1TSHRALDH1A1MAPTKDM4E
SCHEMBL24930641 0.80 MAPT (0.38) L3MBTL1TSHRALDH1A1MAPTKDM4E
SCHEMBL24930600 0.80 MAPT (0.38) L3MBTL1TSHRALDH1A1MAPTKDM4E
SCHEMBL24930845 0.80 MAPT (0.38) L3MBTL1TSHRALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 — — US disclosed
US-11387417-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-07-12 — — US disclosed
US-20210043848-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-02-11 — — US disclosed
US-20210028369-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-28 — — US disclosed
US-20200235307-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2020-07-23 — — US disclosed
US-20200207712-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 — — US disclosed
US-20200207713-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387417-B2 Organic electroluminescent device L3MBTL4, SLC39A14, CTCF L3MBTL1 7/4885TSHR 4596/4885ALDH1A1 1852/4885
US-20210028369-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LIMS1, TERT, TELO2 L3MBTL1 114/4885TSHR 4828/4885ALDH1A1 3470/4885
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, SOD1, TELO2 L3MBTL1 48/4885TSHR 4361/4885ALDH1A1 858/4885
US-20210043848-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LIMS1, TERT, TELO2 L3MBTL1 71/4885TSHR 4806/4885ALDH1A1 2791/4885
US-20200207713-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 L3MBTL1 48/4885TSHR 4361/4885ALDH1A1 858/4885
US-20200207712-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 L3MBTL1 48/4885TSHR 4361/4885ALDH1A1 858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback