SCHEMBL22171879

SCHEMBL22171879

c1ccc(-c2nc3ccccc3nc2-c2oc3cccc4c3c2-c2ccccc2-c2ccccc2-4)cc1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.46
▸ LMNA P02545 5/20 0.46
▸ ALDH1A1 P00352 5/20 0.46
▸ GAA P10253 2/20 0.46
▸ L3MBTL1 Q9Y468 6/20 0.45
▸ KMT2A Q03164 3/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ PKM P14618 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39
▸ AKT1 P31749 1/20 0.37
▸ AKT2 P31751 1/20 0.37
▸ SMN1; SMN2 Q16637 1/20 0.37
▸ ATM Q13315 1/20 0.36
▸ TLR9 Q9NR96 1/20 0.36
▸ THRB P10828 1/20 0.35
▸ CASP1 P29466 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ NR4A2 P43354 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22171877 0.81 MEN1 (0.45) KDM4ELMNAALDH1A1GAAL3MBTL1
SCHEMBL22171993 0.80 MEN1 (0.44) KDM4ELMNAALDH1A1GAAL3MBTL1
SCHEMBL22171878 0.78 L3MBTL1 (0.38) KDM4ELMNAALDH1A1L3MBTL1KMT2A
SCHEMBL20863775 0.77 L3MBTL1 (0.40) KDM4ELMNAALDH1A1GAAL3MBTL1
SCHEMBL22171893 0.77 PLA2G2A (0.37) KDM4ELMNAALDH1A1GAAL3MBTL1
SCHEMBL21366604 0.77 MEN1 (0.48) KDM4ELMNAALDH1A1L3MBTL1KMT2A
SCHEMBL22171871 0.75 MEN1 (0.40) KDM4ELMNAALDH1A1GAAL3MBTL1
SCHEMBL24741045 0.74 CYP1A2 (0.50) KDM4ELMNAALDH1A1GAAL3MBTL1
SCHEMBL22171897 0.74 MEN1 (0.35) KDM4ELMNAALDH1A1L3MBTL1KMT2A
SCHEMBL21366607 0.74 MEN1 (0.36) KDM4ELMNAALDH1A1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2023-02-21 — — US disclosed
US-11387417-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. 2022-07-12 — — US disclosed
US-20210043848-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-02-11 — — US disclosed
US-20210028369-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2021-01-28 — — US disclosed
US-20200235307-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2020-07-23 — — US disclosed
US-20200207712-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 — — US disclosed
US-20200207713-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2020-07-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11387417-B2 Organic electroluminescent device L3MBTL4, SLC39A14, CTCF KDM4E 3013/4885LMNA 1379/4885ALDH1A1 1852/4885
US-20210028369-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LIMS1, TERT, TELO2 KDM4E 3862/4885LMNA 2174/4885ALDH1A1 3470/4885
US-11584719-B2 Organic electroluminescent compound and organic electroluminescent device comprising the same ELAVL1, SOD1, TELO2 KDM4E 1410/4885LMNA 2270/4885ALDH1A1 858/4885
US-20210043848-A1 COMPOSITION MATERIAL FOR ORGANIC ELECTROLUMINESCENT DEVICE, PLURALITY OF HOST MATERIALS, AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME LIMS1, TERT, TELO2 KDM4E 3789/4885LMNA 2090/4885ALDH1A1 2791/4885
US-20200207713-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 KDM4E 1410/4885LMNA 2270/4885ALDH1A1 858/4885
US-20200207712-A1 ORGANIC ELECTROLUMINESCENT COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ELAVL1, SOD1, TELO2 KDM4E 1410/4885LMNA 2270/4885ALDH1A1 858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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