Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 6/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.34 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.34 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905508 | 0.84 | KIF11 (0.36) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL60519 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL192055 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL272417 | 0.73 | KIF11 (0.43) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL972400 | 0.73 | CYP2A6 (0.32) | — | |
| SCHEMBL192799 | 0.73 | ALDH1A1 (0.35) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL596857 | 0.73 | ACHE (0.32) | — | |
| SCHEMBL6223209 | 0.73 | KIF11 (0.38) | ALDH1A1TSHRKIF11 | |
| SCHEMBL21268187 | 0.73 | KIF11 (0.43) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL15353345 | 0.73 | NOTUM (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 987 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230381142-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | US | claimed |
| WO-2023230217-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 2023-11-30 | — | — | WO | claimed |
| CN-115737651-A | Triazine derivatives as interferon-gamma inhibitors | 格林威治大学 | 2023-03-07 | — | — | CN | claimed |
| CN-115385957-A | Linear terphenyl aryl phosphine ligand and transition metal complex thereof | 东莞市均成高新材料有限公司 | 2022-11-25 | — | — | CN | claimed |
| CN-113105486-A | Borate compound and pharmaceutically acceptable salt thereof, and preparation method and application thereof | 南京师范大学 | 2021-07-13 | — | — | CN | claimed |
| EP-3172264-B1 | NOVEL POLYMERS CONTAINING GRAFTED BIS(SULFONYL)IMIDE SODIUM OR LITHIUM SALTS TO THE METHODS FOR THE PRODUCTION THEREOF, AND TO THE USES OF SAME AS ELECTROLYTES FOR BATTERIES | CDP INNOVATION (FR) | 2021-06-16 | — | — | EP | claimed |
| US-20210161873-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | Sanford Burnham Prebys Medical Discovery Institute | 2021-06-03 | — | — | US | claimed |
| US-10576086-B2 | Triazine derivatives as interferon-gamma inhibitors | UNIVERSITY OF GREENWICH (GB) | 2020-03-03 | — | — | US | claimed |
| US-20180169105-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | UNIVERSITY OF GREENWICH (GB) | 2018-06-21 | — | — | US | claimed |
| EP-3307273-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | University of Greenwich (GB) | 2018-04-18 | — | — | EP | claimed |
| WO-1999033828-A1 | BENZO[C]QUINOLIZINE DERIVATIVES AND THEIR USE AS 5 ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1999-07-08 | — | — | WO | claimed |
| EP-0926148-A1 | Benzo (C)quinolizine derivatives, their preparation and use as 5-alphareductases inhibitors | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1999-06-30 | — | — | EP | claimed |
| WO-1999021563-A1 | PREVENTION OF PRECIPITATED ACUTE URINARY RETENTION | MERCK & CO., INC. (US) | 1999-05-06 | — | — | WO | claimed |
| EP-0880520-A1 | BENZO [C]QUINOLIZINE DERIVATIVES, THEIR PREPARATION AND USE AS 5-ALPHA-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1998-12-02 | — | — | EP | claimed |
| US-5707997-A | ANALGESICS | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1998-01-13 | — | — | US | claimed |
| WO-1997029107-A1 | BENZO[C]QUINOLIZINE DERIVATIVES, THEIR PREPARATION AND USE AS 5α-REDUCTASES INHIBITORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 1997-08-14 | — | — | WO | claimed |
| EP-0714898-A1 | PYRAZOLO [1,5-a]PYRIMIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-06-05 | — | — | EP | claimed |
| US-4968341-A | PRE-AND POSTEMERGENCE HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO. (JP) | 1990-11-06 | — | — | US | claimed |
| EP-0183174-B1 | SUBSTITUTED PHENOXY UREA, PROCESSES FOR ITS PREPARATION AND HERBICIDE CONTAINING IT AS ACTIVE INGREDIENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1988-10-26 | — | — | EP | claimed |
| EP-0183174-A2 | Substituted phenoxy urea, processes for its preparation and herbicide containing it as active ingredient | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1986-06-04 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230381142-A1 | ANTILEISHMANIAL COMPOUNDS, COMPOSITIONS AND USE THEREOF | MPO, SSB, SGMS2 | ALDH1A1 3079/4885TSHR 3625/4885KIF11 3219/4885 |
| US-20210161873-A1 | SMALL MOLECULE ACTIVATORS OF NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE (NAMPT) AND USES THEREOF | NAMPT, NAPRT, NNT | ALDH1A1 1943/4885TSHR 3541/4885KIF11 4561/4885 |
| US-10576086-B2 | Triazine derivatives as interferon-gamma inhibitors | IFNG, IFNAR1, IRF3 | ALDH1A1 1809/4885TSHR 498/4885KIF11 4087/4885 |
| US-20180169105-A1 | TRIAZINE DERIVATIVES AS INTERFERON-GAMMA INHIBITORS | IFNG, IFNAR1, IRF3 | ALDH1A1 1809/4885TSHR 498/4885KIF11 4087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.