Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29415188 | 0.86 | MMP1 (0.50) | LTA4HMMP1MMP13SMN1; SMN2HIF1A | |
| SCHEMBL22190045 | 0.84 | SMN1; SMN2 (0.62) | KIF11KMT2ASMN1; SMN2HIF1ACES2 | |
| Methane SCHEMBL29238356 | 0.82 | SMN1; SMN2 (0.60) | KIF11KMT2ASMN1; SMN2HIF1ACES2 | |
| SCHEMBL17964411 | 0.80 | LTA4H (0.55) | KIF11KMT2ALTA4HSMN1; SMN2 | |
| SCHEMBL15553813 | 0.80 | KMT2A (0.51) | KIF11KMT2ALTA4HUSP2TP53 | |
| SCHEMBL7384803 | 0.79 | LDHA (0.51) | LTA4HLDHASMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL15553272 | 0.79 | CHRM1 (0.47) | KMT2ALTA4HUSP2TP53 | |
| SCHEMBL8976499 | 0.78 | LTA4H (0.52) | KIF11KMT2ALTA4HMMP1MMP13 | |
| SCHEMBL1424653 | 0.78 | BLM (0.67) | KMT2AUSP2MMP1MMP13LDHA | |
| SCHEMBL1970323 | 0.78 | MEN1 (0.65) | KIF11KMT2ALDHAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806426-A1 | Process for the preparation of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1997-11-12 | — | — | EP | disclosed |
| EP-0801069-A1 | Process for the preparation of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1997-10-15 | — | — | EP | disclosed |
| EP-0747383-A2 | Polyamine salts of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1996-12-11 | — | — | EP | disclosed |
| EP-0672670-A1 | Process for the preparation of clavulanic acid | SMITHKLINE BEECHAM PLC (GB) | 1995-09-20 | — | — | EP | disclosed |