Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.39 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22374010 | 0.84 | CCNC (0.39) | UHRF1CCNCCDK8PSEN1PSEN2 | |
| SCHEMBL22193555 | 0.83 | ACVR2A (0.44) | DYRK1AMTORAAK1 | |
| SCHEMBL22374090 | 0.81 | MYC (0.39) | TLR8TLR7TLR9AAK1 | |
| SCHEMBL25505853 | 0.77 | TRPA1 (0.47) | UHRF1CCNCCDK8PSEN1PSEN2 | |
| SCHEMBL22681023 | 0.77 | PSEN1 (0.46) | CCNCCDK8PSEN1PSEN2APH1B | |
| SCHEMBL21105125 | 0.74 | RPS6KA3 (0.54) | UHRF1CCNCCDK8PSEN1PSEN2 | |
| SCHEMBL21646546 | 0.71 | NLRP3 (0.44) | DYRK1AAAK1 | |
| SCHEMBL20743706 | 0.70 | TDO2 (0.39) | CCNCCDK8PSEN1PSEN2APH1B | |
| SCHEMBL30684113 | 0.70 | TDO2 (0.39) | CCNCCDK8PSEN1PSEN2APH1B | |
| SCHEMBL1896511 | 0.70 | DYRK1A (0.65) | UHRF1CCNCCDK8PSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11518739-B2 | Sulfonamide carboxamide compounds | INFLAZOME LIMITED (IE) | 2022-12-06 | — | — | US | disclosed |
| US-20200216389-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | INFLAZOME LIMITED (IE) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216389-A1 | NOVEL SULFONAMIDE CARBOXAMIDE COMPOUNDS | NLRP3, NOD1, PYCARD | UHRF1 2416/4885CCNC 3298/4885CDK8 2686/4885 |
| US-11518739-B2 | Sulfonamide carboxamide compounds | NLRP3, PYCARD, NOD1 | UHRF1 2197/4885CCNC 3254/4885CDK8 2828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.