Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | POLB | P06746 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | PRKCH | P24723 | 1/20 | 0.48 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201384 | 0.97 | PRKCH (0.51) | ALDH1A1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL22201385 | 0.92 | KDM4E (0.50) | ALDH1A1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL22201379 | 0.81 | NPC1 (0.50) | ALDH1A1KDM4ESMN1; SMN2MAPK1NPSR1 | |
| SCHEMBL22201452 | 0.81 | PRKCH (0.58) | ALDH1A1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL22201637 | 0.78 | PRKCH (0.50) | ALDH1A1KDM4EMAPTRXFP1MAPK1 | |
| SCHEMBL22201369 | 0.75 | LMNA (0.63) | ALDH1A1KDM4EPOLBMAPTLMNA | |
| SCHEMBL22201641 | 0.75 | RIPK2 (0.55) | PRKCHPRKCESYK | |
| SCHEMBL22201449 | 0.74 | PRKCH (0.51) | ALDH1A1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL22201642 | 0.74 | PRKCH (0.53) | ALDH1A1KDM4EPOLBMAPTSMN1; SMN2 | |
| SCHEMBL22201469 | 0.73 | FGFR2 (0.62) | MAPTLMNAHPGDPRKCHPRKCE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |