Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCH | P24723 | 1/20 | 0.50 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 9/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201413 | 0.82 | ABCG2 (0.53) | ALDH1A1KDM4ERXFP1ABCG2 | |
| SCHEMBL22201452 | 0.82 | PRKCH (0.58) | PRKCHPRKCEALDH1A1MAPTSYK | |
| SCHEMBL22201604 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPTMEN1KMT2ATGFBR1 | |
| SCHEMBL22201384 | 0.80 | PRKCH (0.51) | PRKCHPRKCEALDH1A1MAPTTP53 | |
| SCHEMBL22201638 | 0.79 | KMT2A (0.57) | PRKCHPRKCEALDH1A1MAPTMEN1 | |
| SCHEMBL22201386 | 0.78 | ALDH1A1 (0.51) | PRKCHPRKCEALDH1A1MAPTMEN1 | |
| SCHEMBL22201642 | 0.78 | PRKCH (0.53) | PRKCHPRKCEALDH1A1MAPTSYK | |
| SCHEMBL22201695 | 0.77 | ALDH1A1 (0.49) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL22201634 | 0.77 | TGFBR1 (0.54) | PRKCHPRKCESYKTGFBR1 | |
| SCHEMBL22201369 | 0.77 | LMNA (0.63) | PRKCHPRKCEALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |