Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 7/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.37 |
| ▸ | MTOR | P42345 | 4/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.34 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201239 | 0.87 | PDE5A (0.39) | USP2KMT2AABCB1ABCG2 | |
| SCHEMBL22201537 | 0.85 | KDM4E (0.42) | MEN1KMT2APDE10A | |
| SCHEMBL22201415 | 0.82 | PIP4K2A (0.37) | MEN1KMT2A | |
| SCHEMBL22201236 | 0.81 | KDM4E (0.36) | MEN1KMT2A | |
| SCHEMBL22201365 | 0.81 | ADORA3 (0.38) | MEN1KMT2A | |
| SCHEMBL22201242 | 0.79 | HTR2C (0.38) | MEN1KMT2AABCB1ABCG2HCRTR1 | |
| SCHEMBL22201273 | 0.78 | SYK (0.37) | MEN1KMT2AHCRTR1 | |
| SCHEMBL22201481 | 0.78 | CSF1R (0.37) | MEN1USP2KMT2APDE10AABCB1 | |
| SCHEMBL22201368 | 0.77 | SYK (0.45) | MEN1KMT2APDE10AABCB1ABCG2 | |
| SCHEMBL22201226 | 0.76 | PRKCH (0.37) | KDM1APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |