Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP4K2A | P48426 | 2/20 | 0.37 |
| ▸ | PIP4K2C | Q8TBX8 | 2/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | P2RX3 | P56373 | 5/20 | 0.36 |
| ▸ | TYK2 | P29597 | 7/20 | 0.35 |
| ▸ | JAK3 | P52333 | 7/20 | 0.35 |
| ▸ | JAK2 | O60674 | 5/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201236 | 0.88 | KDM4E (0.36) | TGFBR1P2RX3TYK2JAK3JAK2 | |
| SCHEMBL22201537 | 0.86 | KDM4E (0.42) | PIP4K2APIP4K2CTGFBR1P2RX3ALDH1A1 | |
| SCHEMBL22201239 | 0.84 | PDE5A (0.39) | TGFBR1P2RX3TYK2JAK3JAK2 | |
| SCHEMBL22201416 | 0.82 | MEN1 (0.44) | MEN1KMT2A | |
| SCHEMBL22201242 | 0.82 | HTR2C (0.38) | PIP4K2APIP4K2CTGFBR1P2RX3PRKD1 | |
| SCHEMBL22201365 | 0.82 | ADORA3 (0.38) | TGFBR1P2RX3TYK2JAK3JAK2 | |
| SCHEMBL22201319 | 0.80 | CYP1A2 (0.42) | TGFBR1P2RX3PRKD1ALDH1A1ALOX12 | |
| SCHEMBL22201368 | 0.80 | SYK (0.45) | TGFBR1P2RX3PRKD1ALDH1A1ALOX12 | |
| SCHEMBL22201586 | 0.79 | PRKCH (0.47) | TGFBR1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL22201392 | 0.78 | ALOX12 (0.40) | TGFBR1P2RX3PRKD1ALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |