Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.35 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201239 | 0.91 | PDE5A (0.39) | KMT2ATGFBR1P2RX3CYP1A2GRM4 | |
| SCHEMBL22201236 | 0.87 | KDM4E (0.36) | KDM4EKMT2AMEN1TGFBR1P2RX3 | |
| SCHEMBL22201586 | 0.86 | PRKCH (0.47) | KDM4EKMT2AMEN1TGFBR1ROCK2 | |
| SCHEMBL22201365 | 0.86 | ADORA3 (0.38) | KDM4EKMT2AMEN1TGFBR1P2RX3 | |
| SCHEMBL22201415 | 0.86 | PIP4K2A (0.37) | KDM4EKMT2AMEN1TGFBR1P2RX3 | |
| SCHEMBL22201416 | 0.85 | MEN1 (0.44) | KMT2AMEN1PDE10A | |
| SCHEMBL22201368 | 0.82 | SYK (0.45) | KMT2AMEN1TGFBR1P2RX3CYP1A2 | |
| SCHEMBL22201366 | 0.81 | MAPT (0.39) | KDM4EKMT2AMEN1CYP1A2HPGD | |
| SCHEMBL22201226 | 0.81 | PRKCH (0.37) | TGFBR1P2RX3CYP1A2GRM4ADORA3 | |
| SCHEMBL22201489 | 0.81 | SYK (0.37) | KDM4EKMT2AMEN1TGFBR1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |