Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | TYK2 | P29597 | 2/20 | 0.36 |
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | CD38 | P28907 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201537 | 0.91 | KDM4E (0.42) | PDE5ACYP1A2ALDH1A1LMNACYP3A4 | |
| SCHEMBL22201236 | 0.87 | KDM4E (0.36) | TYK2JAK3JAK2JAK1ALDH1A1 | |
| SCHEMBL22201416 | 0.87 | MEN1 (0.44) | ABCG2USP2KMT2AABCB1 | |
| SCHEMBL22201365 | 0.86 | ADORA3 (0.38) | TYK2JAK3JAK2JAK1CSF1R | |
| SCHEMBL22201366 | 0.85 | MAPT (0.39) | ABCG2CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL22201415 | 0.84 | PIP4K2A (0.37) | TYK2JAK3JAK2JAK1CYP1A2 | |
| SCHEMBL22201481 | 0.83 | CSF1R (0.37) | CSF1RABCG2CYP1A2ALDH1A1USP2 | |
| SCHEMBL22201226 | 0.81 | PRKCH (0.37) | CYP1A2P2RX3GRM4ADORA3TGFBR1 | |
| SCHEMBL22201586 | 0.81 | PRKCH (0.47) | PDE5AABCG2ALDH1A1LMNAKMT2A | |
| SCHEMBL22201368 | 0.81 | SYK (0.45) | ABCG2CYP1A2ALDH1A1P2RX3GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |